Ageing-Associated Genes in Model Organisms
Found 202 results. Showing results 1 to 200.
Entrez ID | Symbol | Name | Organism | Longevity influence | Max average lifespan change | More details |
---|---|---|---|---|---|---|
42186 | 14-3-3epsilon | CG31196 gene product from transcript CG31196-RA | Drosophila melanogaster | Anti-Longevity | 49% | 14-3-3epsilon |
40575 | 5-HT2A | 5-hydroxytryptamine (serotonin) receptor 2A | Drosophila melanogaster | Anti-Longevity | 90% | 5-HT2A |
38342 | AhcyL1 | Adenosylhomocysteinase like 1 | Drosophila melanogaster | Anti-Longevity | 13% | AhcyL1 |
42043 | AhcyL2 | Adenosylhomocysteinase like 2 | Drosophila melanogaster | Anti-Longevity | 21% | AhcyL2 |
41957 | Akt1 | CG4006 gene product from transcript CG4006-RA | Drosophila melanogaster | Pro-Longevity | 11% | Akt1 |
31957 | alpha-Man-I | Alpha Mannosidase I | Drosophila melanogaster | Anti-Longevity | 39% | alpha-Man-I |
39454 | Atg1 | Autophagy-specific gene 1 | Drosophila melanogaster | Pro-Longevity | 25% | Atg1 |
38344 | Atg2 | Autophagy-specific gene 2 | Drosophila melanogaster | Pro-Longevity | 28% | Atg2 |
37141 | Atg7 | Autophagy-specific gene 7 | Drosophila melanogaster | Pro-Longevity | Atg7 | |
32001 | Atg8a | Autophagy-related 8a | Drosophila melanogaster | Pro-Longevity | Atg8a | |
36760 | ATPCL | ATP citrate lyase | Drosophila melanogaster | Anti-Longevity | 32% | ATPCL |
40044 | Aut1 | Aut1 -CG6877 gene product from transcript CG6877-RA | Drosophila melanogaster | Pro-Longevity | 28% | Aut1 |
35900 | babo | baboon | Drosophila melanogaster | Anti-Longevity | 16% | babo |
43038 | bam | bag of marbles | Drosophila melanogaster | Pro-Longevity | 50% | bam |
33819 | bchs | blue cheese | Drosophila melanogaster | Pro-Longevity | 45% | bchs |
39322 | Bmcp | Bmcp | Drosophila melanogaster | Anti-Longevity | Bmcp | |
44801 | bsk | basket | Drosophila melanogaster | Pro-Longevity | 16% | bsk |
32947 | car | carnation | Drosophila melanogaster | Pro-Longevity | car | |
40048 | Cat | Catalase | Drosophila melanogaster | Pro-Longevity | 33% | Cat |
33081 | Cbs | Cystathionine beta-synthase | Drosophila melanogaster | Pro-Longevity | 43% | Cbs |
117353 | Cct1 | CTP:phosphocholine cytidylyltransferase 1 | Drosophila melanogaster | Pro-Longevity | 8% | Cct1 |
36727 | Cdk5 | Cyclin-dependent kinase 5 | Drosophila melanogaster | Pro-Longevity | 33% | Cdk5 |
38928 | cert | ceramide transfer protein | Drosophila melanogaster | Pro-Longevity | cert | |
35751 | CG11165 | CG11165 | Drosophila melanogaster | Pro-Longevity | 54% | CG11165 |
38100 | CG13890 | CG13890 | Drosophila melanogaster | Pro-Longevity | 31% | CG13890 |
32955 | CG14207 | CG14207-PA | Drosophila melanogaster | Pro-Longevity | 5% | CG14207 |
43369 | CG17856 | CG17856 gene product from transcript CG17856-RA | Drosophila melanogaster | Anti-Longevity | 18% | CG17856 |
59170 | CG18809 | CG18809 gene product from transcript CG18809-RA | Drosophila melanogaster | Anti-Longevity | 19% | CG18809 |
33231 | CG2789 | CG2789 | Drosophila melanogaster | Anti-Longevity | 27% | CG2789 |
37996 | CG3776 | Juvenile hormone esterase binding protein 29 (DmP29) | Drosophila melanogaster | Anti-Longevity | 43% | CG3776 |
37996 | CG3776 | Juvenile hormone esterase binding protein 29 (DmP29) | Drosophila melanogaster | Pro-Longevity | 39% | CG3776 |
7354421 | CG42358 | CG42358 | Drosophila melanogaster | Anti-Longevity | CG42358 | |
39761 | CG5389 | CG5389 gene product from transcript CG5389-RA | Drosophila melanogaster | Anti-Longevity | 11% | CG5389 |
32565 | CG9172 | CG9172 gene product from transcript CG9172-RA | Drosophila melanogaster | Anti-Longevity | 46% | CG9172 |
32328 | CG9940 | CG9940 | Drosophila melanogaster | Pro-Longevity | CG9940 | |
42066 | cher | cheerio | Drosophila melanogaster | Pro-Longevity | 9% | cher |
64880 | chico | Insulin receptor substrate-1 | Drosophila melanogaster | Anti-Longevity | 48% | chico |
43928 | chm | chameau | Drosophila melanogaster | Anti-Longevity | 24% | chm |
31647 | cm | carmine | Drosophila melanogaster | Pro-Longevity | cm | |
40988 | Coq2 | Coenzyme Q biosynthesis protein 2 | Drosophila melanogaster | Anti-Longevity | 31% | Coq2 |
34592 | crol | crooked legs | Drosophila melanogaster | Anti-Longevity | 27% | crol |
33474 | daw | dawdle | Drosophila melanogaster | Anti-Longevity | 35% | daw |
36543 | DJ-1alpha | DJ-1alpha | Drosophila melanogaster | Pro-Longevity | DJ-1alpha | |
43652 | dj-1beta | dj-1beta | Drosophila melanogaster | Pro-Longevity | dj-1beta | |
33906 | DLP | Daxx-like protein | Drosophila melanogaster | Pro-Longevity | 20% | DLP |
31310 | dm | diminutive | Drosophila melanogaster | Anti-Longevity | 47% | dm |
3772064 | DNApol-gamma35 | DNA polymerase Gamma | Drosophila melanogaster | Anti-Longevity | 52% | DNApol-gamma35 |
31309 | dnc | dunce | Drosophila melanogaster | Anti-Longevity | dnc | |
31118 | dor | deep orange | Drosophila melanogaster | Pro-Longevity | dor | |
33432 | dpp | decapentaplegic | Drosophila melanogaster | Pro-Longevity | 29% | dpp |
33445 | Drp1 | Dynamin related protein 1 | Drosophila melanogaster | Pro-Longevity | 21% | Drp1 |
42327 | Dys | Dystrophin | Drosophila melanogaster | Pro-Longevity | Dys | |
39203 | E(z) | Enhancer of zeste | Drosophila melanogaster | Anti-Longevity | 76% | E(z) |
35540 | EcR | Ecdysone receptor | Drosophila melanogaster | Anti-Longevity | 50% | EcR |
31154 | Edem1 | CG3810 gene product from transcript CG3810-RC | Drosophila melanogaster | Anti-Longevity | 30% | Edem1 |
36271 | Ef1alpha48D | Elongation factor 148D | Drosophila melanogaster | Pro-Longevity | 41% | Ef1alpha48D |
36242 | Egm | enigma | Drosophila melanogaster | Anti-Longevity | Egm | |
39675 | Eip71CD | Ecdysone-induced protein 28/29kD | Drosophila melanogaster | Pro-Longevity | 70% | Eip71CD |
31000 | elav | embryonic lethal abnormal vision | Drosophila melanogaster | Pro-Longevity | 66% | elav |
34595 | esc | extra sexcombs | Drosophila melanogaster | Anti-Longevity | 59% | esc |
34903 | esg | escargot | Drosophila melanogaster | Anti-Longevity | 21% | esg |
3772232 | fabp | fatty acid bindin protein | Drosophila melanogaster | Pro-Longevity | 81% | fabp |
31845 | fh | frataxin homolog | Drosophila melanogaster | Pro-Longevity | 35% | fh |
43383 | fkh | fork head | Drosophila melanogaster | Pro-Longevity | 14% | fkh |
41709 | foxo | Forkhead box, sub-group O | Drosophila melanogaster | Pro-Longevity | 33% | foxo |
45374 | fwd | four wheel drive | Drosophila melanogaster | Pro-Longevity | 9% | fwd |
44819 | g | garnet | Drosophila melanogaster | Pro-Longevity | g | |
35646 | Gadd45 | CG11086 gene product from transcript CG11086-RA | Drosophila melanogaster | Pro-Longevity | 77% | Gadd45 |
53581 | Gclc | Glutamate-cysteine ligase catalytic subunit | Drosophila melanogaster | Pro-Longevity | 50% | Gclc |
248194 | Gclm | Glutamate-cysteine ligase modifier subunit | Drosophila melanogaster | Pro-Longevity | 24% | Gclm |
40201 | gig | gigas | Drosophila melanogaster | Pro-Longevity | gig | |
36447 | GLaz | Glial Lazarillo | Drosophila melanogaster | Pro-Longevity | GLaz | |
33386 | GlyP | Glycogen phosphorylase | Drosophila melanogaster | Anti-Longevity | 17% | GlyP |
41823 | GlyS | Glycogen synthase | Drosophila melanogaster | Anti-Longevity | 10% | GlyS |
41561 | Gnmt | Glycine N-methyltransferase | Drosophila melanogaster | Pro-Longevity | Gnmt | |
33824 | Gpdh | Glycerol 3 phosphate dehydrogenase | Drosophila melanogaster | Anti-Longevity | 20% | Gpdh |
38453 | Gr63a | Gustatory receptor 63a | Drosophila melanogaster | Anti-Longevity | 30% | Gr63a |
36927 | GstS1 | Glutathione S transferase S1 | Drosophila melanogaster | Pro-Longevity | 33% | GstS1 |
36011 | hebe | hebe gene product from transcript hebe-RD | Drosophila melanogaster | Pro-Longevity | 24% | hebe |
45875 | Hex-A | Hexokinase A | Drosophila melanogaster | Anti-Longevity | 10% | Hex-A |
44008 | Hex-C | Hexokinase C | Drosophila melanogaster | Anti-Longevity | Hex-C | |
35169 | hk | hook | Drosophila melanogaster | Pro-Longevity | hk | |
32080 | hop | hopscotch | Drosophila melanogaster | Pro-Longevity | hop | |
32133 | Hsc70-3 | Heat shock protein cognate 3 | Drosophila melanogaster | Pro-Longevity | 27% | Hsc70-3 |
3772576 | Hsp22 | Heat shock protein 22 | Drosophila melanogaster | Unclear | Hsp22 | |
39075 | Hsp26 | Heat shock protein 26 | Drosophila melanogaster | Pro-Longevity | 30% | Hsp26 |
39078 | Hsp27 | Heat shock protein 27 | Drosophila melanogaster | Pro-Longevity | 30% | Hsp27 |
39071 | Hsp67Bc | Heat shock gene 67Bc | Drosophila melanogaster | Pro-Longevity | 6% | Hsp67Bc |
42852 | Hsp68 | Heat shock protein 68 | Drosophila melanogaster | Pro-Longevity | 20% | Hsp68 |
hsp70 | Heat Shock Protein | Drosophila melanogaster | Pro-Longevity | hsp70 | ||
44921 | Hsp70Ba | Heat shock 70kDa protein 1A | Drosophila melanogaster | Unclear | Hsp70Ba | |
53573 | Ilk | Integrin linked kinase | Drosophila melanogaster | Anti-Longevity | 63% | Ilk |
39150 | Ilp2 | Insulin-related peptide | Drosophila melanogaster | Anti-Longevity | 47% | Ilp2 |
31220 | Ilp6 | Insulin-like peptide 6 | Drosophila melanogaster | Pro-Longevity | 16% | Ilp6 |
38513 | ImpL2 | Ecdysone-inducible gene L2 | Drosophila melanogaster | Pro-Longevity | 23% | ImpL2 |
32343 | inaE | inactivation no afterpotential E | Drosophila melanogaster | Pro-Longevity | 73% | inaE |
40049 | Indy | I'm not dead yet protein | Drosophila melanogaster | Anti-Longevity | 92% | Indy |
42549 | InR | Insulin-like 1 receptor | Drosophila melanogaster | Anti-Longevity | 85% | InR |
42358 | Ire1 | Inositol-requiring enzyme-1 | Drosophila melanogaster | Pro-Longevity | Ire1 | |
53578 | Jafrac1 | Thioredoxin peroxidase 1 | Drosophila melanogaster | Pro-Longevity | 29% | Jafrac1 |
34624 | JhI-21 | CG12317-PA | Drosophila melanogaster | Anti-Longevity | 32% | JhI-21 |
42062 | Keap1 | CG3962 gene product from transcript CG3962-RA | Drosophila melanogaster | Anti-Longevity | 10% | Keap1 |
46027 | kermit | CG11546 | Drosophila melanogaster | Pro-Longevity | 30% | kermit |
40680 | kra | krasavietz | Drosophila melanogaster | Anti-Longevity | 25% | kra |
42063 | kuk | kugelkern | Drosophila melanogaster | Anti-Longevity | kuk | |
249462 | l(3)DTS3 | lethal (3) DTS3 | Drosophila melanogaster | Anti-Longevity | 42% | l(3)DTS3 |
46260 | l(3)neo18 | l(3)neo18 | Drosophila melanogaster | Anti-Longevity | 24% | l(3)neo18 |
37482 | LBR | Lamin B receptor | Drosophila melanogaster | Anti-Longevity | LBR | |
12798012 | let-7 | let-7 | Drosophila melanogaster | Unannotated | let-7 | |
43130 | Lnk | CG17367 gene product from transcript CG17367-RC | Drosophila melanogaster | Anti-Longevity | 33% | Lnk |
42672 | loco | locomotion defects | Drosophila melanogaster | Anti-Longevity | loco | |
3355130 | lt | light | Drosophila melanogaster | Pro-Longevity | lt | |
33529 | Mad | Mothers against dpp | Drosophila melanogaster | Pro-Longevity | 22% | Mad |
36048 | magu | magu gene product from transcript magu -RD | Drosophila melanogaster | Pro-Longevity | 5% | magu |
47173 | Men | Malic enzyme | Drosophila melanogaster | Pro-Longevity | 45% | Men |
12798013 | mir-125 | mir-125 stem loop | Drosophila melanogaster | Pro-Longevity | mir-125 | |
12798384 | mir-14 | mir-14 stem loop | Drosophila melanogaster | Pro-Longevity | mir-14 | |
12798434 | mir-184 | mir-184 stem loop | Drosophila melanogaster | Anti-Longevity | mir-184 | |
12798086 | mir-277 | mir-277 stem loop | Drosophila melanogaster | Anti-Longevity | 70% | mir-277 |
12798087 | mir-34 | mir-34 stem loop | Drosophila melanogaster | Pro-Longevity | mir-34 | |
35523 | mle | Maleless | Drosophila melanogaster | Pro-Longevity | 48% | mle |
40849 | Mlp84B | Muscle LIM protein at 84B | Drosophila melanogaster | Pro-Longevity | 35% | Mlp84B |
31331 | Mnt | CG13316-PC, isoform C | Drosophila melanogaster | Pro-Longevity | Mnt | |
42866 | Mpk2 | CG5475-PA | Drosophila melanogaster | Pro-Longevity | 40% | Mpk2 |
41387 | Mrp4 | Multidrug resistance protein 4 ortholog | Drosophila melanogaster | Pro-Longevity | Mrp4 | |
34632 | Mt2 | DNA methyltransferase 2 | Drosophila melanogaster | Pro-Longevity | Mt2 | |
39089 | MTF-1 | Metal response element-binding Transcription Factor-1 | Drosophila melanogaster | Pro-Longevity | 40% | MTF-1 |
38058 | mth | methuselah | Drosophila melanogaster | Unclear | 35% | mth |
40436 | mub | mushroom-body expressed | Drosophila melanogaster | Anti-Longevity | 21% | mub |
43811 | myo | myoglianin | Drosophila melanogaster | Pro-Longevity | 25% | myo |
44885 | mys | myospheroid | Drosophila melanogaster | Anti-Longevity | 44% | mys |
42348 | Naam | Naam gene product from transcript Naam-RA | Drosophila melanogaster | Pro-Longevity | 30% | Naam |
31762 | ND75 | NADH:ubiquinone reductase 75kD subunit precursor | Drosophila melanogaster | Anti-Longevity | 15% | ND75 |
43149 | Nf1 | Neurofibromin 1 | Drosophila melanogaster | Pro-Longevity | 68% | Nf1 |
33324 | NLaz | Neural Lazarillo | Drosophila melanogaster | Pro-Longevity | 31% | NLaz |
47895 | Nmdmc | NAD-dependent methylenetetrahydrofolate dehydrogenase | Drosophila melanogaster | Pro-Longevity | 120% | Nmdmc |
42018 | NPF | neuropeptide F | Drosophila melanogaster | Anti-Longevity | 25% | NPF |
40650 | Orco | Odorant receptor co-receptor | Drosophila melanogaster | Anti-Longevity | 56% | Orco |
5009 | OTC | ornithine carbamoyltransferase | Drosophila melanogaster | Pro-Longevity | 21% | OTC |
31429 | ovo | CG6824-PA | Drosophila melanogaster | Anti-Longevity | 50% | ovo |
34780 | p38b | CG7393-PA | Drosophila melanogaster | Pro-Longevity | 60% | p38b |
2768677 | p53 | CG33336-PA | Drosophila melanogaster | Anti-Longevity | 58% | p53 |
40336 | park | parkin | Drosophila melanogaster | Pro-Longevity | 28% | park |
40668 | Pcmt | Protein-L-isoaspartate (D-aspartate) O-methyltransferase | Drosophila melanogaster | Pro-Longevity | 39% | Pcmt |
40293 | Pex16 | peroxin 16 | Drosophila melanogaster | Pro-Longevity | 75% | Pex16 |
31143 | Pgam5 | Phosphoglycerate mutase 5 | Drosophila melanogaster | Pro-Longevity | 9% | Pgam5 |
42446 | Pi3K92E | CG4141 gene product from transcript CG4141-RA | Drosophila melanogaster | Pro-Longevity | 5% | Pi3K92E |
31607 | Pink1 | PTEN-induced putative kinase 1 | Drosophila melanogaster | Pro-Longevity | 18% | Pink1 |
34284 | Pka-C1 | cAMP-dependent protein kinase 1 | Drosophila melanogaster | Pro-Longevity | Pka-C1 | |
36990 | POSH | Plenty of SH3s | Drosophila melanogaster | Pro-Longevity | 14% | POSH |
32731 | ppk23 | pickpocket 23 | Drosophila melanogaster | Anti-Longevity | 4% | ppk23 |
32671 | ppk28 | pickpocket 28 | Drosophila melanogaster | Anti-Longevity | 44% | ppk28 |
37123 | Prp19 | Pre-RNA processing factor 19 | Drosophila melanogaster | Pro-Longevity | 25% | Prp19 |
3771951 | Prx5 | Peroxiredoxin 5 | Drosophila melanogaster | Pro-Longevity | 30% | Prx5 |
43991 | Pten | CG5671 gene product from transcript CG5671-RB | Drosophila melanogaster | Pro-Longevity | 13% | Pten |
40958 | puc | puckered | Drosophila melanogaster | Anti-Longevity | puc | |
31381 | rb | ruby | Drosophila melanogaster | Pro-Longevity | rb | |
33498 | Rbp9 | RNA-binding protein 9 | Drosophila melanogaster | Pro-Longevity | 33% | Rbp9 |
31826 | rdgA | retinal degeneration A | Drosophila melanogaster | Anti-Longevity | 44% | rdgA |
2769007 | Rdh | CG14975-PA | Drosophila melanogaster | Pro-Longevity | 8% | Rdh |
36281 | rho-7 | rhomboid-7 | Drosophila melanogaster | Pro-Longevity | rho-7 | |
38565 | Rpd3 | CG7471-PA | Drosophila melanogaster | Anti-Longevity | 52% | Rpd3 |
246599 | Rpi | Ribose-5-phosphate isomerase | Drosophila melanogaster | Anti-Longevity | 38% | Rpi |
40002 | RpIIIC53 | RNA polymerase III subunit C53 | Drosophila melanogaster | Anti-Longevity | 11% | RpIIIC53 |
32406 | rut | rutabaga | Drosophila melanogaster | Pro-Longevity | rut | |
41605 | ry | rosy | Drosophila melanogaster | Pro-Longevity | ry | |
38654 | S6k | RPS6-p70-protein kinase | Drosophila melanogaster | Anti-Longevity | S6k | |
31129 | Scgdelta | Sarcoglycan delta | Drosophila melanogaster | Pro-Longevity | 30% | Scgdelta |
35590 | SdhB | Succinate dehydrogenase B | Drosophila melanogaster | Pro-Longevity | 66% | SdhB |
41340 | SdhC | succinate dehydrogenase, cytochrome b556 subunit | Drosophila melanogaster | Pro-Longevity | 22% | SdhC |
34708 | Sir2 | CG5216-PA | Drosophila melanogaster | Pro-Longevity | Sir2 | |
42414 | Sirt2 | CG5085-PA | Drosophila melanogaster | Pro-Longevity | 20% | Sirt2 |
31480 | Sirt4 | Sirtuin 4 | Drosophila melanogaster | Pro-Longevity | 20% | Sirt4 |
41254 | Sirt6 | CG6284-PB | Drosophila melanogaster | Pro-Longevity | 20% | Sirt6 |
31738 | Smox | Smad on X | Drosophila melanogaster | Anti-Longevity | 10% | Smox |
43904 | SNF1A | SNF1A/AMP-activated protein kinase | Drosophila melanogaster | Pro-Longevity | 20% | SNF1A |
42515 | SNF4Agamma | SNF4/AMP-activated protein kinase gamma subunit | Drosophila melanogaster | Pro-Longevity | 23% | SNF4Agamma |
31704 | snz | snazarus (sorting nexin lazarus) | Drosophila melanogaster | Anti-Longevity | 85% | snz |
39251 | Sod | Superoxide dismutase | Drosophila melanogaster | Pro-Longevity | Sod | |
36878 | Sod2 | Superoxide dismutase 2 (Mn) | Drosophila melanogaster | Pro-Longevity | Sod2 | |
40562 | Spargel | Spargel | Drosophila melanogaster | Pro-Longevity | 33% | Spargel |
42428 | Stat92E | Signal-transducer and activator of transcription protein at 92E | Drosophila melanogaster | Pro-Longevity | 33% | Stat92E |
34119 | Su(var)205 | Suppressor of variegation 205 | Drosophila melanogaster | Pro-Longevity | Su(var)205 | |
36424 | sug | sugarbabe | Drosophila melanogaster | Pro-Longevity | 9% | sug |
44046 | sun | Stunted | Drosophila melanogaster | Anti-Longevity | sun | |
44498 | Surf1 | surfeit gene 1 | Drosophila melanogaster | Anti-Longevity | Surf1 | |
39048 | teq | Tequila | Drosophila melanogaster | Anti-Longevity | 31% | teq |
33569 | Thor | CG8846 gene product from transcript CG8846-RA | Drosophila melanogaster | Pro-Longevity | 22% | Thor |
43036 | to | takeout | Drosophila melanogaster | Pro-Longevity | 26% | to |
35236 | Top3alpha | Topoisomerase 3alpha | Drosophila melanogaster | Pro-Longevity | 20% | Top3alpha |
47396 | Tor | Target of rapamycin | Drosophila melanogaster | Anti-Longevity | Tor | |
38065 | trh | trachealess | Drosophila melanogaster | Anti-Longevity | 90% | trh |
34281 | Trx-2 | thioredoxin-2 | Drosophila melanogaster | Pro-Longevity | Trx-2 | |
31760 | Trxr-1 | Thioredoxin reductase-1 | Drosophila melanogaster | Pro-Longevity | Trxr-1 | |
31443 | TrxT | Thioredoxin T | Drosophila melanogaster | Pro-Longevity | 15% | TrxT |
42862 | Tsc1 | CG6147-PA Tuberous sclerosis complex genes 1 | Drosophila melanogaster | Pro-Longevity | Tsc1 | |
35615 | Tsp42Ef | Tetraspanin 42Ef | Drosophila melanogaster | Anti-Longevity | 18% | Tsp42Ef |
7351 | UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | Drosophila melanogaster | Pro-Longevity | 30% | UCP2 |
34997 | VhaSFD | Vacuolar H+-ATPase SFD subunit | Drosophila melanogaster | Pro-Longevity | 10% | VhaSFD |
31201 | Vinc | Vinculin | Drosophila melanogaster | Pro-Longevity | 150% | Vinc |