GenAge entry for Atg7 (Drosophila melanogaster)
Gene information (ID: 21)
- Symbol
- Atg7
- Aliases
- atg-7; atg7; CG5489; Dmel\CG5489
- Name
- Autophagy-specific gene 7
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Involved in autophagy
Potential relevance to longevity and/or ageing
- Observations
- Knockouts are short-lived and hypersensitive to nutrient and oxidative stress. There is a 30% reduction in maximal lifespan.
- % change in max lifespan
- Maximal lifespan is 30% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Mutants are hypersensitive to oxidative stress and short lived.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenDR gene manipulations
- CellAge
- A homolog of this gene for Homo sapiens is present as ATG7
Homologs in other organisms
- Caenorhabditis elegans
- atg-7
- Danio rerio
- atg7
- Homo sapiens
- ATG7
- Mus musculus
- Atg7
- Rattus norvegicus
- Atg7
- Saccharomyces cerevisiae
- ATG7
- Schizosaccharomyces pombe
- atg7
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (37141)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar