Drosophila melanogasterGenAge entry for Mlp84B (Drosophila melanogaster)

Gene information (ID: 869)

Symbol
Mlp84B
Aliases
CG1019; DLim-3; Dmel\CG1019; DmLIM-3; dMlp84B; Mlmu84B;
Name
Muscle LIM protein at 84B
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Male flies expressing mlp84B RNAi in the heart display bradycardia and heart rhythm abnormalities and have a shortened mean lifespan compared with controls. No lifespan reduction was observed in females.
% change in avg or median lifespan
Median male lifespan is approximately 35% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference, Knockdown
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    mlp-1
    Danio rerio
    csrp1b
    Danio rerio
    csrp1a
    Danio rerio
    csrp2
    Danio rerio
    csrp3
    Homo sapiens
    CSRP2
    Homo sapiens
    CSRP1
    Homo sapiens
    CSRP3
    Mus musculus
    Csrp3
    Mus musculus
    Csrp1
    Mus musculus
    Csrp2
    Rattus norvegicus
    Csrp3
    Rattus norvegicus
    Csrp1
    Rattus norvegicus
    Csrp2

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (40849)
    Homologues
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    UniProt
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    Internet
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