GenAge entry for AhcyL2 (Drosophila melanogaster)
Gene information (ID: 2085)
- Symbol
- AhcyL2
- Name
- Adenosylhomocysteinase like 2
- Organism
- Drosophila melanogaster (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Downregulation of two out of three of Drosophila homologs of AHCY significantly extended life span in adult males and females, median lifespan was 21% higher when Ahcy89E was downregulated. Intestine specific downregulation of Ahcy89E resulted in increased lifespan and health span.
- % change in avg or median lifespan
- Median lifespan is 21% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as AHCYL2
Homologs in other organisms
- Danio rerio
- AHCYL2 (1 of many)
- Danio rerio
- ahcyl2
- Danio rerio
- ahcyl1
- Homo sapiens
- AHCYL2
- Homo sapiens
- AHCYL1
- Mus musculus
- Ahcyl1
- Mus musculus
- Ahcyl2
- Rattus norvegicus
- Ahcyl1
- Rattus norvegicus
- Ahcyl2
- Saccharomyces cerevisiae
- SAH1
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (42043)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar