Drosophila melanogasterGenAge entry for S6k (Drosophila melanogaster)

Gene information (ID: 583)

Symbol
S6k
Aliases
10539; 7084; CG10539; Dmel\CG10539; dp70s6k; Dp70s6k; Dp
Name
RPS6-p70-protein kinase
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Part of the TOR pathway involved in cell growth and size

Potential relevance to longevity and/or ageing

Observations
Expression of a dominant-negative form extended lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Dominant negative mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Rps6kb1
    • A homolog of this gene for Caenorhabditis elegans is present as rsks-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as TPK3
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as RPS6KB1
    CellAge
    • A homolog of this gene for Homo sapiens is present as RPS6KB1

    Homologs in other organisms

    Caenorhabditis elegans
    rsks-1
    Danio rerio
    rps6kb1b
    Danio rerio
    rps6kb1a
    Homo sapiens
    RPS6KB2
    Homo sapiens
    RPS6KB1
    Mus musculus
    Rps6kb1
    Mus musculus
    Rps6kb2
    Rattus norvegicus
    Rps6kb2
    Rattus norvegicus
    Rps6kb1
    Saccharomyces cerevisiae
    TPK3

    External links

    FlyBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (38654)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar