March 17, 2010

GenAge build 15 was released. This latest build is mostly a data update and features 261 manually-curated human genes and 789 genes in model organisms. Further details are available in the release notes.

August 13, 2009

A new description of AnAge has been published in the Journal of Evolutionary Biology (22(8):1770-1774). This work details aspects of data collection, organization and quality assessment as well as some new features in AnAge and its potential uses in a broad range of biological disciplines. It becomes the official citation of works that only employ AnAge.

May 7, 2009

AnAge build 11 was released. This build is a qualitative improvement. No new species were added, but several improvements were made to existing entries. For more details, please consult the release notes.

April 30, 2009

By combining ageing gene expression profiles from different tissues in mice, rats and humans, conserved molecular signatures of ageing were derived. These signatures reveal genes and processes consistently over- or underexpressed with age including previously unknown transcriptional changes with age. Further details as well as the full results are available online.

February 16, 2009

An updated description of HAGR and of its uses has been published in Aging Cell (8(1):65-72). This more recent description of HAGR details numerous enhancements and becomes the official citation of HAGR or of any of its resources.

July 20, 2008

GenAge build 14 was released. This latest build features 261 manually-curated human genes, 789 genes in model organisms, and an updated bibliography. Further details are available in the release notes.

April 18, 2008

AnAge build 10 was released, featuring 4,122 entries. In addition to numerous updates and additions, this build features vastly improved data for birds. For more details, please consult the release notes.

December 17, 2007

Through demographic parameters, namely the slope of the mortality curve, it is possible to estimate the rate of ageing of a given population, which can be useful to compare the rate of ageing between species or between animal cohorts used in experiments. A method to obtain such estimates of the ageing rate, as well as an SPSS script to aid in the calculations, is now described in the software section.

June 20, 2007

An extensive list of genes analyzed for their possible association with human longevity has been included in GenAge. While genes associated with human longevity have been featured before in GenAge, this latest dataset with over 200 genes tested for their possible association with human longevity and/or survival in old age represents a major update.

February 7, 2007

In addition to GenAge's putative human ageing-related genes, GenAge now features genes related to longevity and/or ageing in model organisms. In build 13 released today, 411 genes from model organisms are included. This expansion of GenAge was done in collaboration with Vadim Fraifeld who is now a curator for GenAge. Further details about build 13 are available in the release notes.

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24.04.2009 - Study identifies genes that protect against ageing (University of Liverpool press release)

17.02.2009 - Scientists develop resource to study animal ageing (University of Liverpool press release)

12.03.2007 - Metabolic Rate Is Not Associated with Longevity

10.11.2005 - Mitochondrial Optimization May Be Linked to Human Longevity

07.25.2005 - Development Causes Aging

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