Ageing-Associated Genes in Model Organisms

Found 193 results. Showing results 1 to 193.

Entrez ID Symbol Name Organism Longevity influence Max average lifespan change More details
42186 14-3-3epsilon CG31196 gene product from transcript CG31196-RA Drosophila melanogaster Anti-Longevity 49% Increase 14-3-3epsilon
40575 5-HT2A 5-hydroxytryptamine (serotonin) receptor 2A Drosophila melanogaster Anti-Longevity 90% Increase 5-HT2A
38342 AhcyL1 Adenosylhomocysteinase like 1 Drosophila melanogaster Anti-Longevity 13% Increase AhcyL1
42043 AhcyL2 Adenosylhomocysteinase like 2 Drosophila melanogaster Anti-Longevity 21% Increase AhcyL2
41957 Akt1 CG4006 gene product from transcript CG4006-RA Drosophila melanogaster Pro-Longevity 11% Decrease Akt1
31957 alpha-Man-I Alpha Mannosidase I Drosophila melanogaster Anti-Longevity 39% Increase alpha-Man-I
39454 Atg1 Autophagy-specific gene 1 Drosophila melanogaster Pro-Longevity 25% Increase Atg1
38344 Atg2 Autophagy-specific gene 2 Drosophila melanogaster Pro-Longevity 28% Increase Atg2
37141 Atg7 Autophagy-specific gene 7 Drosophila melanogaster Pro-Longevity Decrease Atg7
32001 Atg8a Autophagy-related 8a Drosophila melanogaster Pro-Longevity Increase and Decrease Atg8a
36760 ATPCL ATP citrate lyase Drosophila melanogaster Anti-Longevity 32% Increase ATPCL
40044 Aut1 Aut1 -CG6877 gene product from transcript CG6877-RA Drosophila melanogaster Pro-Longevity 28% Decrease Aut1
35900 babo baboon Drosophila melanogaster Anti-Longevity 16% Increase babo
43038 bam bag of marbles Drosophila melanogaster Pro-Longevity 50% Increase bam
33819 bchs blue cheese Drosophila melanogaster Pro-Longevity 45% Decrease bchs
39322 Bmcp Bmcp Drosophila melanogaster Anti-Longevity Increase Bmcp
44801 bsk basket Drosophila melanogaster Pro-Longevity 16% Decrease bsk
32947 car carnation Drosophila melanogaster Pro-Longevity Increase car
40048 Cat Catalase Drosophila melanogaster Pro-Longevity 33% Increase Cat
33081 Cbs Cystathionine beta-synthase Drosophila melanogaster Pro-Longevity 43% Increase Cbs
117353 Cct1 CTP:phosphocholine cytidylyltransferase 1 Drosophila melanogaster Pro-Longevity 8% Increase Cct1
36727 Cdk5 Cyclin-dependent kinase 5 Drosophila melanogaster Pro-Longevity 33% Decrease Cdk5
38928 cert ceramide transfer protein Drosophila melanogaster Pro-Longevity Decrease cert
35751 CG11165 CG11165 Drosophila melanogaster Pro-Longevity 54% Increase CG11165
38100 CG13890 CG13890 Drosophila melanogaster Pro-Longevity 31% Increase CG13890
32955 CG14207 CG14207-PA Drosophila melanogaster Pro-Longevity 5% Increase CG14207
43369 CG17856 CG17856 gene product from transcript CG17856-RA Drosophila melanogaster Anti-Longevity 18% Increase CG17856
59170 CG18809 CG18809 gene product from transcript CG18809-RA Drosophila melanogaster Anti-Longevity 19% Increase CG18809
33231 CG2789 CG2789 Drosophila melanogaster Anti-Longevity 27% Increase CG2789
37996 CG3776 Juvenile hormone esterase binding protein 29 (DmP29) Drosophila melanogaster Anti-Longevity 43% Decrease CG3776
37996 CG3776 Juvenile hormone esterase binding protein 29 (DmP29) Drosophila melanogaster Pro-Longevity 39% Decrease CG3776
7354421 CG42358 CG42358 Drosophila melanogaster Anti-Longevity Increase and Decrease CG42358
39761 CG5389 CG5389 gene product from transcript CG5389-RA Drosophila melanogaster Anti-Longevity 11% Increase CG5389
32565 CG9172 CG9172 gene product from transcript CG9172-RA Drosophila melanogaster Anti-Longevity 46% Increase CG9172
32328 CG9940 CG9940 Drosophila melanogaster Pro-Longevity Increase CG9940
42066 cher cheerio Drosophila melanogaster Pro-Longevity 9% Increase cher
64880 chico Insulin receptor substrate-1 Drosophila melanogaster Anti-Longevity 48% Increase chico
43928 chm chameau Drosophila melanogaster Anti-Longevity 24% Increase chm
31647 cm carmine Drosophila melanogaster Pro-Longevity Decrease cm
40988 Coq2 Coenzyme Q biosynthesis protein 2 Drosophila melanogaster Anti-Longevity 31% Increase Coq2
34592 crol crooked legs Drosophila melanogaster Anti-Longevity 27% Increase crol
33474 daw dawdle Drosophila melanogaster Anti-Longevity 35% Increase daw
36543 DJ-1alpha DJ-1alpha Drosophila melanogaster Pro-Longevity Decrease DJ-1alpha
43652 dj-1beta dj-1beta Drosophila melanogaster Pro-Longevity Decrease dj-1beta
33906 DLP Daxx-like protein Drosophila melanogaster Pro-Longevity 20% Decrease DLP
31310 dm diminutive Drosophila melanogaster Anti-Longevity 47% Decrease dm
3772064 DNApol-gamma35 DNA polymerase Gamma Drosophila melanogaster Anti-Longevity 52% Decrease DNApol-gamma35
31309 dnc dunce Drosophila melanogaster Anti-Longevity Increase dnc
31118 dor deep orange Drosophila melanogaster Pro-Longevity Decrease dor
33432 dpp decapentaplegic Drosophila melanogaster Pro-Longevity 29% Decrease dpp
42327 Dys Dystrophin Drosophila melanogaster Pro-Longevity Decrease Dys
39203 E(z) Enhancer of zeste Drosophila melanogaster Anti-Longevity 76% Increase E(z)
35540 EcR Ecdysone receptor Drosophila melanogaster Anti-Longevity 50% Increase EcR
31154 Edem1 CG3810 gene product from transcript CG3810-RC Drosophila melanogaster Anti-Longevity 30% Increase Edem1
36271 Ef1alpha48D Elongation factor 148D Drosophila melanogaster Pro-Longevity 41% Increase Ef1alpha48D
36242 Egm enigma Drosophila melanogaster Anti-Longevity Increase Egm
39675 Eip71CD Ecdysone-induced protein 28/29kD Drosophila melanogaster Pro-Longevity 70% Increase Eip71CD
31000 elav embryonic lethal abnormal vision Drosophila melanogaster Pro-Longevity 66% Decrease elav
34595 esc extra sexcombs Drosophila melanogaster Anti-Longevity 59% Increase esc
34903 esg escargot Drosophila melanogaster Anti-Longevity 21% Increase esg
3772232 fabp fatty acid bindin protein Drosophila melanogaster Pro-Longevity 81% Increase fabp
31845 fh frataxin homolog Drosophila melanogaster Pro-Longevity 35% Increase fh
41709 foxo Forkhead box, sub-group O Drosophila melanogaster Pro-Longevity 33% Increase foxo
45374 fwd four wheel drive Drosophila melanogaster Pro-Longevity 9% Increase fwd
44819 g garnet Drosophila melanogaster Pro-Longevity Decrease g
35646 Gadd45 CG11086 gene product from transcript CG11086-RA Drosophila melanogaster Pro-Longevity 77% Increase Gadd45
53581 Gclc Glutamate-cysteine ligase catalytic subunit Drosophila melanogaster Pro-Longevity 50% Increase Gclc
248194 Gclm Glutamate-cysteine ligase modifier subunit Drosophila melanogaster Pro-Longevity 24% Increase Gclm
40201 gig gigas Drosophila melanogaster Pro-Longevity Increase gig
36447 GLaz Glial Lazarillo Drosophila melanogaster Pro-Longevity Increase and Decrease GLaz
33386 GlyP Glycogen phosphorylase Drosophila melanogaster Anti-Longevity 17% Increase GlyP
41823 GlyS Glycogen synthase Drosophila melanogaster Anti-Longevity 10% Increase GlyS
41561 Gnmt Glycine N-methyltransferase Drosophila melanogaster Pro-Longevity Increase Gnmt
33824 Gpdh Glycerol 3 phosphate dehydrogenase Drosophila melanogaster Anti-Longevity 20% Increase Gpdh
38453 Gr63a Gustatory receptor 63a Drosophila melanogaster Anti-Longevity 30% Increase Gr63a
36927 GstS1 Glutathione S transferase S1 Drosophila melanogaster Pro-Longevity 33% Increase GstS1
36011 hebe hebe gene product from transcript hebe-RD Drosophila melanogaster Pro-Longevity 24% Increase hebe
45875 Hex-A Hexokinase A Drosophila melanogaster Anti-Longevity 10% Increase Hex-A
44008 Hex-C Hexokinase C Drosophila melanogaster Anti-Longevity Increase Hex-C
35169 hk hook Drosophila melanogaster Pro-Longevity Decrease hk
32080 hop hopscotch Drosophila melanogaster Pro-Longevity Increase and Decrease hop
32133 Hsc70-3 Heat shock protein cognate 3 Drosophila melanogaster Pro-Longevity 27% Increase Hsc70-3
3772576 Hsp22 Heat shock protein 22 Drosophila melanogaster Unclear Increase and Decrease Hsp22
39075 Hsp26 Heat shock protein 26 Drosophila melanogaster Pro-Longevity 30% Increase Hsp26
39078 Hsp27 Heat shock protein 27 Drosophila melanogaster Pro-Longevity 30% Increase Hsp27
39071 Hsp67Bc Heat shock gene 67Bc Drosophila melanogaster Pro-Longevity 6% Increase Hsp67Bc
42852 Hsp68 Heat shock protein 68 Drosophila melanogaster Pro-Longevity 20% Increase Hsp68
hsp70 Heat Shock Protein Drosophila melanogaster Pro-Longevity Increase hsp70
44921 Hsp70Ba Heat shock 70kDa protein 1A Drosophila melanogaster Unclear Increase and Decrease Hsp70Ba
53573 Ilk Integrin linked kinase Drosophila melanogaster Anti-Longevity 63% Increase Ilk
39150 Ilp2 Insulin-related peptide Drosophila melanogaster Anti-Longevity 47% Increase Ilp2
31220 Ilp6 Insulin-like peptide 6 Drosophila melanogaster Pro-Longevity 16% Increase Ilp6
38513 ImpL2 Ecdysone-inducible gene L2 Drosophila melanogaster Pro-Longevity 23% Increase ImpL2
32343 inaE inactivation no afterpotential E Drosophila melanogaster Pro-Longevity 73% Increase inaE
40049 Indy I'm not dead yet protein Drosophila melanogaster Anti-Longevity 92% Increase Indy
42549 InR Insulin-like 1 receptor Drosophila melanogaster Anti-Longevity 85% Increase InR
42358 Ire1 Inositol-requiring enzyme-1 Drosophila melanogaster Pro-Longevity Decrease Ire1
53578 Jafrac1 Thioredoxin peroxidase 1 Drosophila melanogaster Pro-Longevity 29% Increase Jafrac1
34624 JhI-21 CG12317-PA Drosophila melanogaster Anti-Longevity 32% Increase JhI-21
42062 Keap1 CG3962 gene product from transcript CG3962-RA Drosophila melanogaster Anti-Longevity 10% Increase Keap1
46027 kermit CG11546 Drosophila melanogaster Pro-Longevity 30% Decrease kermit
40680 kra krasavietz Drosophila melanogaster Anti-Longevity 25% Increase kra
42063 kuk kugelkern Drosophila melanogaster Anti-Longevity Decrease kuk
249462 l(3)DTS3 lethal (3) DTS3 Drosophila melanogaster Anti-Longevity 42% Increase l(3)DTS3
46260 l(3)neo18 l(3)neo18 Drosophila melanogaster Anti-Longevity 24% Increase l(3)neo18
37482 LBR Lamin B receptor Drosophila melanogaster Anti-Longevity Decrease LBR
43130 Lnk CG17367 gene product from transcript CG17367-RC Drosophila melanogaster Anti-Longevity 33% Increase Lnk
42672 loco locomotion defects Drosophila melanogaster Anti-Longevity Increase and Decrease loco
3355130 lt light Drosophila melanogaster Pro-Longevity Decrease lt
33529 Mad Mothers against dpp Drosophila melanogaster Pro-Longevity 22% Decrease Mad
36048 magu magu gene product from transcript magu -RD Drosophila melanogaster Pro-Longevity 5% Increase magu
47173 Men Malic enzyme Drosophila melanogaster Pro-Longevity 45% Increase Men
12798013 mir-125 mir-125 stem loop Drosophila melanogaster Pro-Longevity Decrease mir-125
12798384 mir-14 mir-14 stem loop Drosophila melanogaster Pro-Longevity Decrease mir-14
12798086 mir-277 mir-277 stem loop Drosophila melanogaster Anti-Longevity 70% Increase mir-277
12798087 mir-34 mir-34 stem loop Drosophila melanogaster Pro-Longevity Decrease mir-34
35523 mle Maleless Drosophila melanogaster Pro-Longevity 48% Decrease mle
40849 Mlp84B Muscle LIM protein at 84B Drosophila melanogaster Pro-Longevity 35% Decrease Mlp84B
31331 Mnt CG13316-PC, isoform C Drosophila melanogaster Pro-Longevity Increase and Decrease Mnt
42866 Mpk2 CG5475-PA Drosophila melanogaster Pro-Longevity 40% Decrease Mpk2
41387 Mrp4 Multidrug resistance protein 4 ortholog Drosophila melanogaster Pro-Longevity Increase and Decrease Mrp4
34632 Mt2 DNA methyltransferase 2 Drosophila melanogaster Pro-Longevity Increase Mt2
39089 MTF-1 Metal response element-binding Transcription Factor-1 Drosophila melanogaster Pro-Longevity 40% Increase MTF-1
38058 mth methuselah Drosophila melanogaster Unclear 35% Increase mth
40436 mub mushroom-body expressed Drosophila melanogaster Anti-Longevity 21% Increase mub
43811 myo myoglianin Drosophila melanogaster Pro-Longevity 25% Increase myo
44885 mys myospheroid Drosophila melanogaster Anti-Longevity 44% Increase mys
42348 Naam Naam gene product from transcript Naam-RA Drosophila melanogaster Pro-Longevity 30% Increase Naam
31762 ND75 NADH:ubiquinone reductase 75kD subunit precursor Drosophila melanogaster Anti-Longevity 15% Increase ND75
43149 Nf1 Neurofibromin 1 Drosophila melanogaster Pro-Longevity 68% Increase Nf1
33324 NLaz Neural Lazarillo Drosophila melanogaster Pro-Longevity 31% Decrease NLaz
47895 Nmdmc NAD-dependent methylenetetrahydrofolate dehydrogenase Drosophila melanogaster Pro-Longevity 120% Increase Nmdmc
42018 NPF neuropeptide F Drosophila melanogaster Anti-Longevity 25% Decrease NPF
40650 Orco Odorant receptor co-receptor Drosophila melanogaster Anti-Longevity 56% Increase Orco
31429 ovo CG6824-PA Drosophila melanogaster Anti-Longevity 50% Increase ovo
34780 p38b CG7393-PA Drosophila melanogaster Pro-Longevity 60% Decrease p38b
2768677 p53 CG33336-PA Drosophila melanogaster Anti-Longevity 58% Increase p53
40336 park parkin Drosophila melanogaster Pro-Longevity 28% Increase park
40668 Pcmt Protein-L-isoaspartate (D-aspartate) O-methyltransferase Drosophila melanogaster Pro-Longevity 39% Increase Pcmt
40293 Pex16 peroxin 16 Drosophila melanogaster Pro-Longevity 75% Decrease Pex16
42446 Pi3K92E CG4141 gene product from transcript CG4141-RA Drosophila melanogaster Pro-Longevity 5% Decrease Pi3K92E
31607 Pink1 PTEN-induced putative kinase 1 Drosophila melanogaster Pro-Longevity 18% Increase Pink1
34284 Pka-C1 cAMP-dependent protein kinase 1 Drosophila melanogaster Pro-Longevity Increase Pka-C1
36990 POSH Plenty of SH3s Drosophila melanogaster Pro-Longevity 14% Increase POSH
32731 ppk23 pickpocket 23 Drosophila melanogaster Anti-Longevity 4% Decrease ppk23
32671 ppk28 pickpocket 28 Drosophila melanogaster Anti-Longevity 44% Increase ppk28
3771951 Prx5 Peroxiredoxin 5 Drosophila melanogaster Pro-Longevity 30% Increase Prx5
43991 Pten CG5671 gene product from transcript CG5671-RB Drosophila melanogaster Pro-Longevity 13% Increase Pten
40958 puc puckered Drosophila melanogaster Anti-Longevity Increase puc
31381 rb ruby Drosophila melanogaster Pro-Longevity Decrease rb
33498 Rbp9 RNA-binding protein 9 Drosophila melanogaster Pro-Longevity 33% Decrease Rbp9
31826 rdgA retinal degeneration A Drosophila melanogaster Anti-Longevity 44% Increase rdgA
2769007 Rdh CG14975-PA Drosophila melanogaster Pro-Longevity 8% Increase Rdh
36281 rho-7 rhomboid-7 Drosophila melanogaster Pro-Longevity Decrease rho-7
38565 Rpd3 CG7471-PA Drosophila melanogaster Anti-Longevity 52% Increase Rpd3
246599 Rpi Ribose-5-phosphate isomerase Drosophila melanogaster Anti-Longevity 38% Increase Rpi
32406 rut rutabaga Drosophila melanogaster Pro-Longevity Decrease rut
41605 ry rosy Drosophila melanogaster Pro-Longevity Decrease ry
38654 S6k RPS6-p70-protein kinase Drosophila melanogaster Anti-Longevity Increase S6k
31129 Scgdelta Sarcoglycan delta Drosophila melanogaster Pro-Longevity 30% Decrease Scgdelta
35590 SdhB Succinate dehydrogenase B Drosophila melanogaster Pro-Longevity 66% Decrease SdhB
41340 SdhC succinate dehydrogenase, cytochrome b556 subunit Drosophila melanogaster Pro-Longevity 22% Decrease SdhC
34708 Sir2 CG5216-PA Drosophila melanogaster Pro-Longevity Increase and Decrease Sir2
42414 Sirt2 CG5085-PA Drosophila melanogaster Pro-Longevity 20% Decrease Sirt2
41254 Sirt6 CG6284-PB Drosophila melanogaster Pro-Longevity 20% Decrease Sirt6
31738 Smox Smad on X Drosophila melanogaster Anti-Longevity 10% Increase Smox
43904 SNF1A SNF1A/AMP-activated protein kinase Drosophila melanogaster Pro-Longevity 20% Increase SNF1A
42515 SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit Drosophila melanogaster Pro-Longevity 23% Decrease SNF4Agamma
31704 snz snazarus (sorting nexin lazarus) Drosophila melanogaster Anti-Longevity 85% Increase snz
39251 Sod Superoxide dismutase Drosophila melanogaster Pro-Longevity Increase and Decrease Sod
36878 Sod2 Superoxide dismutase 2 (Mn) Drosophila melanogaster Pro-Longevity Increase and Decrease Sod2
40562 Spargel Spargel Drosophila melanogaster Pro-Longevity 33% Increase Spargel
42428 Stat92E Signal-transducer and activator of transcription protein at 92E Drosophila melanogaster Pro-Longevity 33% Decrease Stat92E
34119 Su(var)205 Suppressor of variegation 205 Drosophila melanogaster Pro-Longevity Increase and Decrease Su(var)205
36424 sug sugarbabe Drosophila melanogaster Pro-Longevity 9% Increase sug
44046 sun Stunted Drosophila melanogaster Anti-Longevity Increase sun
44498 Surf1 surfeit gene 1 Drosophila melanogaster Anti-Longevity Increase Surf1
39048 teq Tequila Drosophila melanogaster Anti-Longevity 31% Increase teq
33569 Thor CG8846 gene product from transcript CG8846-RA Drosophila melanogaster Pro-Longevity 22% Increase Thor
43036 to takeout Drosophila melanogaster Pro-Longevity 26% Increase to
35236 Top3alpha Topoisomerase 3alpha Drosophila melanogaster Pro-Longevity 20% Decrease Top3alpha
47396 Tor Target of rapamycin Drosophila melanogaster Anti-Longevity Increase Tor
38065 trh trachealess Drosophila melanogaster Anti-Longevity 90% Increase trh
34281 Trx-2 thioredoxin-2 Drosophila melanogaster Pro-Longevity Decrease Trx-2
31760 Trxr-1 Thioredoxin reductase-1 Drosophila melanogaster Pro-Longevity Increase Trxr-1
31443 TrxT Thioredoxin T Drosophila melanogaster Pro-Longevity 15% Increase TrxT
42862 Tsc1 CG6147-PA Tuberous sclerosis complex genes 1 Drosophila melanogaster Pro-Longevity Increase Tsc1
35615 Tsp42Ef Tetraspanin 42Ef Drosophila melanogaster Anti-Longevity 18% Increase Tsp42Ef
7351 UCP2 uncoupling protein 2 (mitochondrial, proton carrier) Drosophila melanogaster Pro-Longevity 30% Increase UCP2
34997 VhaSFD Vacuolar H+-ATPase SFD subunit Drosophila melanogaster Pro-Longevity 10% Increase VhaSFD
31201 Vinc Vinculin Drosophila melanogaster Pro-Longevity 150% Increase Vinc
43508 yata CG1973 gene product from transcript CG1973-RA Drosophila melanogaster Pro-Longevity Decrease yata
32974 Zw Zwischenferment Drosophila melanogaster Pro-Longevity 38% Increase Zw