Caenorhabditis elegansGenAge entry for let-60 (Caenorhabditis elegans)

Gene information (ID: 407)

Symbol
let-60
Name
LEThal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Ras homolog

Potential relevance to longevity and/or ageing

Observations
Activating mutations weakly suppress constitutive dauer diapause in daf-2 and age-1 mutants and extend lifespan induced by mutation of daf-2.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as RAS1
    • A homolog of this gene for Saccharomyces cerevisiae is present as RAS2
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HRAS
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as HRAS
    CellAge
    • A homolog of this gene for Homo sapiens is present as HRAS
    • A homolog of this gene for Homo sapiens is present as NRAS
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as NRAS

    Homologs in other organisms

    Danio rerio
    zgc:55558
    Danio rerio
    nras
    Danio rerio
    kras
    Danio rerio
    hrasa
    Danio rerio
    kras
    Danio rerio
    hrasb
    Drosophila melanogaster
    Ras85D
    Homo sapiens
    HRAS
    Homo sapiens
    NRAS
    Homo sapiens
    KRAS
    Mus musculus
    Kras
    Mus musculus
    Hras
    Mus musculus
    Nras
    Rattus norvegicus
    Hras
    Rattus norvegicus
    Kras
    Rattus norvegicus
    Nras
    Rattus norvegicus
    Hras
    Saccharomyces cerevisiae
    RAS1
    Saccharomyces cerevisiae
    RAS2
    Schizosaccharomyces pombe
    ras1

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (178104)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar