GenAge entry for Myc (Mus musculus)
Gene information (ID: 1876)
- Symbol
- Myc
- Name
- myelocytomatosis oncogene
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Haploinsufficient Myc mice are more active, have a higher metabolic rate and healthier lipid metabolism, and display resistance to several age-associated pathologies, including osteoporosis, cardiac fibrosis, and immunosenescence. Additionally, both male and female mutants live longer than the wild type.
- % change in avg or median lifespan
- Male median lifespan is ~10% higher; Female median lifespan is ~21%.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as dm
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MYC
- CellAge
- A homolog of this gene for Homo sapiens is present as MYC
Homologs in other organisms
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (17869)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar