Saccharomyces cerevisiaeGenAge entry for RPS6B (Saccharomyces cerevisiae)

Gene information (ID: 577)

Symbol
RPS6B
Aliases
LPG18; RPS101; RPS102
Name
ribosomal 40S subunit protein S6B
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Protein component of the small (40S) ribosomal subunit

Potential relevance to longevity and/or ageing

Observations
Deletion increased mean replicative lifespan by about 30%.
% change in avg or median lifespan
Average replicative lifespan is about 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Deletion of the SSU RPS6B paralog, but not of the RPS6A paralog increased replicative median life span robustly by 45%
    % change in avg or median lifespan
    Replicative lifespan is 45% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Deletion
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as rps-6
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as RPS6

      Homologs in other organisms

      Caenorhabditis elegans
      rps-6
      Caenorhabditis elegans
      rps-6
      Danio rerio
      rps6
      Danio rerio
      rps6
      Drosophila melanogaster
      RpS6
      Drosophila melanogaster
      RpS6
      Homo sapiens
      RPS6
      Homo sapiens
      RPS6
      Mus musculus
      Rps6
      Mus musculus
      Rps6
      Mus musculus
      Rps6
      Mus musculus
      Rps6
      Rattus norvegicus
      Rps6
      Rattus norvegicus
      Rps6
      Rattus norvegicus
      Rps6
      Rattus norvegicus
      Rps6
      Rattus norvegicus
      AABR07059478.1
      Rattus norvegicus
      AABR07059478.1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (852479)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar