Caenorhabditis elegansGenAge entry for ser-1 (Caenorhabditis elegans)

Gene information (ID: 597)

Symbol
ser-1
Name
SERotonin/octopamine receptor family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serotonin receptor gene

Potential relevance to longevity and/or ageing

Observations
Deletion increased longevity by up to 46%.
% change in avg or median lifespan
Lifespan is up to 46% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as 5-HT2A
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as HTR2A

    Homologs in other organisms

    Danio rerio
    htr2cl1
    Danio rerio
    htr2cl2
    Danio rerio
    htr2b
    Danio rerio
    htr2aa
    Danio rerio
    htr2ab
    Drosophila melanogaster
    5-HT2A
    Homo sapiens
    HTR2B
    Homo sapiens
    HTR2C
    Homo sapiens
    HTR2A
    Mus musculus
    Htr2c
    Mus musculus
    Htr2a
    Mus musculus
    Htr2b
    Rattus norvegicus
    Htr2b
    Rattus norvegicus
    Htr2c
    Rattus norvegicus
    Htr2a

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (181716)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar