- Symbol
- ASF1
- Aliases
- CIA1
- Name
- Anti-Silencing Function
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Yeast lacking Asf1 are short lived, having a median replicative life span of about 7 generations in comparison to the median life span of about 27 generations for wild-type yeast in multiple yeast backgrounds. Asf1 mutants also exhibit some phenotypes characteristic of aging.
- % change in avg or median lifespan
- Replicative lifespan is about 74% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Observations
- Replicative lifespan decreased by 65% in the alpha strain
- % change in avg or median lifespan
- Replicative lifespan is 65% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as ASF1A
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as ASF1B
- Caenorhabditis elegans
- unc-85
- Caenorhabditis elegans
- asfl-1
- Danio rerio
- asf1bb
- Danio rerio
- asf1ba
- Drosophila melanogaster
- asf1
- Homo sapiens
- ASF1A
- Homo sapiens
- ASF1B
- Mus musculus
- Asf1b
- Mus musculus
- Asf1a
- Rattus norvegicus
- Asf1b
- Rattus norvegicus
- Asf1a
- Schizosaccharomyces pombe
- cia1
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (853327)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for ASF1 (Saccharomyces cerevisiae)