GenAge entry for EPOR (Homo sapiens)
Gene name (HAGRID: 52)
- HGNC symbol
- EPOR
- Aliases
- EPO-R
- Common name
- Erythropoietin receptor
Potential relevance to the human ageing process
- Main reason for selection
- Entry selected based on evidence showing that the gene product to be a target of genes previously linked to ageing
- Description
EPOR is a member of the cytokine receptor family. Its dysregulation may affect the growth of certain tumours. EPOR is involved in inflammation and has been related to age-related changes [383]. It has not been shown to play a major role in ageing, though.
Cytogenetic information
- Cytogenetic band
- 19p13.2
- Location
- 11,377,204 bp to 11,384,341 bp
- Orientation
- Minus strand
Protein information
- Gene Ontology
-
Process: GO:0007165; signal transduction
GO:0007420; brain development
GO:0007507; heart development
GO:0046697; decidualization
Cellular component: GO:0005576; extracellular region
GO:0005887; integral component of plasma membrane
Show all GO termsFunction: GO:0004900; erythropoietin receptor activity
GO:0042802; identical protein binding
Protein interactions and network
- Protein-protein interacting partners in GenAge
- SHC1, PTPN11, STAT5A, IRS2, GRB2, PIK3R1, JAK2, SOCS2
- STRING interaction network
Retrieve sequences for EPOR
Homologs in model organisms
In other databases
- CellAge
- This gene is present as EPOR
Selected references
External links
- EPD
- ORF Accession
- NM_000121
- CDS Accession
- NP_000112
- OMIM
- 133171
- HPRD
- Ensembl
- EPOR
- UniProt/Swiss-Prot
- EPOR_HUMAN
- GeneCards
- EPOR
- Entrez Gene
- 2057
- GenAtlas
- EPOR
- Internet
- Search Google