Caenorhabditis elegansGenAge entry for akt-1 (Caenorhabditis elegans)

Gene information (ID: 10)

Symbol
akt-1
Name
AKT kinase family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Signal transduction

Potential relevance to longevity and/or ageing

Observations
Knockdown of akt-1 increased lifespan.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNA interference leads to lifespan extension.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
      • A homolog of this gene for Drosophila melanogaster is present as Akt1
      • A homolog of this gene for Saccharomyces cerevisiae is present as YPK1
      • A homolog of this gene for Mus musculus is present as Akt1
      • A homolog of this gene for Mus musculus is present as Akt2
      GenAge human genes
      • A homolog of this gene for Homo sapiens is present as AKT1
      GenDR gene manipulations
      • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as AKT1
      • A homolog of this gene for Homo sapiens is present as AKT3
      CellAge
      • A homolog of this gene for Homo sapiens is present as AKT1
      • A homolog of this gene for Homo sapiens is present as AKT3

      Homologs in other organisms

      Danio rerio
      akt3b
      Danio rerio
      akt3a
      Danio rerio
      akt2
      Danio rerio
      AKT1
      Danio rerio
      akt2l
      Drosophila melanogaster
      Akt1
      Homo sapiens
      AKT1
      Homo sapiens
      AKT3
      Homo sapiens
      AKT2
      Mus musculus
      Akt3
      Mus musculus
      Akt1
      Mus musculus
      Akt2
      Rattus norvegicus
      Akt3
      Rattus norvegicus
      Akt2
      Rattus norvegicus
      Akt1
      Saccharomyces cerevisiae
      SCH9
      Saccharomyces cerevisiae
      YPK2
      Saccharomyces cerevisiae
      YPK1

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (179424)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar