Drosophila melanogasterGenAge entry for Akt1 (Drosophila melanogaster)

Gene information (ID: 832)

Symbol
Akt1
Aliases
akt; Akt; AKT; Akt/PKB; AKT/PKB; akt1; AKT1; Akt1|PKB; CG4
Name
CG4006 gene product from transcript CG4006-RA
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of Akt in intestinal stem cells, results in impaired regeneration of the intestinal epithelium and are shorten lifespan.
% change in avg or median lifespan
Average male lifespan is 11.4% lower; Average female lifespan is 7.4% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as akt-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPK1
    • A homolog of this gene for Mus musculus is present as Akt1
    • A homolog of this gene for Mus musculus is present as Akt2
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as AKT1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as AKT1
    • A homolog of this gene for Homo sapiens is present as AKT3
    CellAge
    • A homolog of this gene for Homo sapiens is present as AKT1

    Homologs in other organisms

    Caenorhabditis elegans
    akt-2
    Caenorhabditis elegans
    akt-1
    Danio rerio
    akt2
    Danio rerio
    akt3a
    Danio rerio
    akt3b
    Danio rerio
    akt2l
    Danio rerio
    AKT1
    Homo sapiens
    AKT3
    Homo sapiens
    AKT1
    Homo sapiens
    AKT2
    Mus musculus
    Akt2
    Mus musculus
    Akt1
    Mus musculus
    Akt3
    Rattus norvegicus
    Akt3
    Rattus norvegicus
    Akt1
    Rattus norvegicus
    Akt2
    Saccharomyces cerevisiae
    SCH9
    Saccharomyces cerevisiae
    YPK1
    Saccharomyces cerevisiae
    YPK2
    Schizosaccharomyces pombe
    sck1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (41957)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar