GenAge Human Genes
This section of GenAge features genes possibly related to human ageing. It is designed to help researchers study the genetic basis of ageing using functional genomics approaches. All entries are the result of considerable manually-curated annotation.
Briefly, genes were selected for inclusion largely based on findings in model organisms. As such, they are classified as putative cases of genes associated with human ageing. All entries were constructed based on an extensive review of the literature and the reason why each gene is featured is given in each entry, in addition to other bibliographical references. Detailed information concerning the creation and selection of human genes can be found elsewhere.
Finding Entries
Searching is simple and intuitive. Just type your search query to look for a gene. You can enter one or more words from the gene's name or use the gene's HGNC symbol. Note that the search is case insensitive.
You may also list all human genes in the database or find genes in a specific chromosomal location.
Using the Bibliography
Although GenAge is not an exhaustive bibliographical database, you may browse or search its literature:
Other Tools and Datasets
Of interest to researchers is also a manually curated list of genes analyzed for their possible association with human longevity.
A microarray sourced database of genes commonly altered during ageing is also available for search.
It is possible to analyse a subset of genes. You can also view GenAge's statistics. A network analysis of GenAge, and the first protein network analysis of human ageing was previously published.
Download
You may download a zipped tab-delimited ASCII dataset with all genes, derived from the latest stable build of GenAge. For practical reasons sequences were excluded, though all other data is included.
Feedback
If you find an error or wish to propose another gene to be included in the database, please contact us. To receive the latest news and announcements, please join the HAGR-news mailing list.