GenAge entry for NDE1 (Saccharomyces cerevisiae)
Gene information (ID: 455)
- Symbol
- NDE1
- Aliases
- NDH1
- Name
- NADH-ubiquinone reductase (H(+)-translocating) NDE1
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Mitochondrial electron transport chain
Potential relevance to longevity and/or ageing
- Observations
- Overexpression of Nde1 and Nde2 resulted in a longer replicative lifespan (20-25%) on 2% glucose, but not on 0.5% glucose.
- % change in avg or median lifespan
- Replicative lifespan is 20-25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Chronological lifespan extension
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenDR gene manipulations
- This gene is present as NDE1
Homologs in other organisms
No homologs found
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (855176)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar