GenAge entry for daf-14 (Caenorhabditis elegans)
Gene information (ID: 158)
- Symbol
- daf-14
- Name
- abnormal DAuer Formation
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Possibly a transducer of the DAF-7/TGF-beta-mediated signal that promotes reproductive growth and ne
Potential relevance to longevity and/or ageing
- Observations
- Mutation in adults increased mean lifespan by up to 44% and maximum lifespan by 50%.
- % change in max lifespan
- Maximum lifespan is 50% higher.
- % change in avg or median lifespan
- Average lifespan is up to 44% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
- Danio rerio
- si:dkey-222b8.1
- Danio rerio
- SMAD4 (1 of many)
- Danio rerio
- si:dkey-239n17.4
- Danio rerio
- smad4a
- Drosophila melanogaster
- Med
- Homo sapiens
- SMAD4
- Mus musculus
- Smad4
- Rattus norvegicus
- Smad4
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (177908)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar