Mus musculusGenAge entry for Chek2 (Mus musculus)

Gene information (ID: 122)

Symbol
Chek2
Aliases
CHK2; Cds1; Rad53; HUCDS1
Name
CHK2 checkpoint homolog (S. pombe)
Organism
Mus musculus (AnAge)
Known functions and activities
Cell cycle checkpoint regulator

Potential relevance to longevity and/or ageing

Observations
Mice hypomorphic for Brca1 and double mutant for chk2 exhibit signs of premature ageing.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as CHEK2
    CellAge
    • A homolog of this gene for Homo sapiens is present as CHEK2

    Homologs in other organisms

    Caenorhabditis elegans
    chk-2
    Caenorhabditis elegans
    T08D2.7
    Danio rerio
    chek2
    Drosophila melanogaster
    lok
    Homo sapiens
    CHEK2
    Rattus norvegicus
    Chek2
    Saccharomyces cerevisiae
    RAD53
    Schizosaccharomyces pombe
    cds1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (50883)
    Homologues
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    UniProt
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    Internet
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