GenAge entry for ule-5 (Caenorhabditis elegans)
Gene information (ID: 2160)
- Symbol
- ule-5
- Name
- Uterine Lumin Expressed/locailized
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Worms overexpressing ule-5 demonstrated a decrease in median lifespan (27%) when compared to the control. Two expression lines were used. These results were consistent for other uterine proteins. Additionally, simultaneous downregulation of ule-3, ule-4, ule-5, and ule-2 increased lifespan by 15-20% compared to the control.
- % change in avg or median lifespan
- Median lifespan is 27% higher.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
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- Ensembl
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- Entrez Gene
- View on Entrez Gene database (181365)
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar