Caenorhabditis elegansGenAge entry for sca-1 (Caenorhabditis elegans)

Gene information (ID: 587)

Symbol
sca-1
Name
SERCA (Sarco-Endoplasmic Reticulum Calcium ATPase)
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Required for development and muscle function

Potential relevance to longevity and/or ageing

Observations
RNA interference of sca-1 results in an increased lifespan.
% change in avg or median lifespan
Mean lifespan is 18.6% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNA interference extends lifespan.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      atp2a3
      Drosophila melanogaster
      Ca-P60A
      Homo sapiens
      ATP2A3
      Mus musculus
      Atp2a3
      Rattus norvegicus
      Atp2a3

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176512)
      Homologues
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      UniProt
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      Internet
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