- Symbol
- hlh-30
- Name
- Helix Loop Helix
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Worms overexpressing hlh-30 demonstrated a 15-20% increase in mean lifespan when compared to the wild type. This lifespan extension was linked to induction of autophagy.
- % change in avg or median lifespan
- Mean lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge
- A homolog of this gene for Homo sapiens is present as MITF
- Danio rerio
- tfe3a
- Danio rerio
- tfec
- Danio rerio
- tfeb
- Danio rerio
- tfe3b
- Danio rerio
- mitfb
- Danio rerio
- mitfa
- Drosophila melanogaster
- Mitf
- Homo sapiens
- TFE3
- Homo sapiens
- MITF
- Homo sapiens
- TFEC
- Homo sapiens
- TFEB
- Mus musculus
- Tfe3
- Mus musculus
- Mitf
- Mus musculus
- Tfeb
- Mus musculus
- Tfec
- Rattus norvegicus
- Mitf
- Rattus norvegicus
- Tfe3
- Rattus norvegicus
- Tfec
- Rattus norvegicus
- Tfeb
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (177157)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for hlh-30 (Caenorhabditis elegans)