Caenorhabditis elegansGenAge entry for dkf-2 (Caenorhabditis elegans)

Gene information (ID: 180)

Symbol
dkf-2
Name
D Kinase Family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serine/threonine protein kinase PKC mu/PKD

Potential relevance to longevity and/or ageing

Observations
Adult median and maximal lifespan increases by 40% and 20%, respectively, in animals lacking dkf-2. dkf-2 deficiency also ameliorated heat stress.
% change in max lifespan
Maximum lifespan is 20% higher.
% change in avg or median lifespan
Average lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as PRKD1
    • A homolog of this gene for Homo sapiens is present as PRKD2

    Homologs in other organisms

    Danio rerio
    prkd2
    Danio rerio
    pimr39
    Danio rerio
    zgc:175248
    Danio rerio
    prkd1
    Danio rerio
    prkd3
    Danio rerio
    CR847936.11
    Danio rerio
    CABZ01072853.1
    Homo sapiens
    PRKD3
    Homo sapiens
    PRKD1
    Homo sapiens
    PRKD2
    Mus musculus
    Prkd1
    Mus musculus
    Prkd3
    Mus musculus
    Prkd2
    Rattus norvegicus
    Prkd3
    Rattus norvegicus
    Prkd2
    Rattus norvegicus
    Prkd1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180121)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar