Caenorhabditis elegansGenAge entry for dkf-2 (Caenorhabditis elegans)

Gene information (ID: 180)

Symbol
dkf-2
Name
D Kinase Family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serine/threonine protein kinase PKC mu/PKD

Potential relevance to longevity and/or ageing

Observations
Adult median and maximal lifespan increases by 40% and 20%, respectively, in animals lacking dkf-2. dkf-2 deficiency also ameliorated heat stress.
% change in max lifespan
Maximum lifespan is 20% higher.
% change in avg or median lifespan
Average lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    prkd1
    Drosophila melanogaster
    PKD
    Homo sapiens
    PRKD2
    Mus musculus
    Prkd2
    Rattus norvegicus
    Prkd2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180121)
    Homologues
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    UniProt
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    Internet
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