Drosophila melanogasterGenAge entry for cm (Drosophila melanogaster)

Gene information (ID: 133)

Symbol
cm
Aliases
ap-3; AP-3; AP3mu3; cg3035; CG3035; CG32731; Dmel\CG3035
Name
carmine
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
u-subunit of AP-3 complex

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutation reduces maximum lifespan by 40%.
% change in max lifespan
Maximal lifespan is 40% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as APM1

    Homologs in other organisms

    Caenorhabditis elegans
    apm-3
    Danio rerio
    ap3m1
    Danio rerio
    ap3m2
    Homo sapiens
    AP3M1
    Homo sapiens
    AP3M2
    Mus musculus
    Ap3m2
    Mus musculus
    Ap3m1
    Rattus norvegicus
    Ap3m1
    Rattus norvegicus
    Ap3m2
    Saccharomyces cerevisiae
    APM1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (31647)
    Homologues
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    UniProt
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    Internet
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