Caenorhabditis elegansGenAge entry for ccr-4 (Caenorhabditis elegans)

Gene information (ID: 97)

Symbol
ccr-4
Name
CCR (yeast CCR4/NOT complex component) homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Alcohol dehydrogenase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 33% in wild type animals, 37% in a daf-2 background and 44% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 33% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    zgc:171797
    Drosophila melanogaster
    twin
    Mus musculus
    Cnot6
    Rattus norvegicus
    Cnot6
    Saccharomyces cerevisiae
    NGL1
    Schizosaccharomyces pombe
    ccr4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178184)
    Homologues
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    UniProt
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    Internet
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