Drosophila melanogasterGenAge entry for car (Drosophila melanogaster)

Gene information (ID: 89)

Symbol
car
Aliases
Car; carn; CG12230; Dm-Vps33; Dmel\CG12230; l(1)G0447; V
Name
carnation
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Vps 33, sec1 protein

Potential relevance to longevity and/or ageing

Observations
Loss-of-function mutation results in a 30% maximum lifespan reduction.
% change in max lifespan
Maximal lifespan is 30% lower.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as vps-33.1

    Homologs in other organisms

    Caenorhabditis elegans
    vps-33.1
    Danio rerio
    vps33a
    Homo sapiens
    VPS33A
    Homo sapiens
    0
    Mus musculus
    Vps33a
    Rattus norvegicus
    Vps33a
    Saccharomyces cerevisiae
    VPS33
    Schizosaccharomyces pombe
    vps33

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (32947)
    Homologues
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    UniProt
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    Internet
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