Caenorhabditis elegansGenAge entry for bar-1 (Caenorhabditis elegans)

Gene information (ID: 39)

Symbol
bar-1
Name
beta-catenin
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Multifunctional protein involved in development and transcriptional regulation

Potential relevance to longevity and/or ageing

Observations
May play a role in regulating daf-16 during dauer formation, particularly in conditions of oxidative stress. Deletion of bar-1 reduces mean (45%) and maximal (35%) lifespan.
% change in max lifespan
Maximum lifespan is 35% lower.
% change in avg or median lifespan
Average lifespan is 45% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    No homologs found

    External links

    WormBase
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    Entrez Gene
    View on Entrez Gene database (180982)
    Homologues
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    UniProt
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    Internet
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