Saccharomyces cerevisiaeGenAge entry for SET2 (Saccharomyces cerevisiae)

Gene information (ID: 1585)

Symbol
SET2
Aliases
EZL1
Name
SET domain-containing
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of histone methyltransferase SET2 results in an increased replicative lifespan.
% change in avg or median lifespan
Replicative lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan decreased by 15% in the alpha strain
    % change in avg or median lifespan
    Replicative lifespan is 15% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      Homologs in other organisms

      Schizosaccharomyces pombe
      set2

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (853271)
      Homologues
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      UniProt
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      Internet
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