GenAge entry for Dmd (Mus musculus)
Gene information (ID: 815)
- Symbol
- Dmd
- Aliases
- dys; mdx; pke; Dp71; Dp427; DXSmh7; DXSmh9
- Name
- Dystrophin, muscular dystrophy
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Reduction in lifespan and displayed a progressively dystrophic muscle histopathology. Old mdx mice were also prone to develop muscle tumors that resembled the human form of alveolar rhabdomyosarcoma.
- % change in max lifespan
- Maximum lifespan is 22% lower.
- % change in avg or median lifespan
- Average female lifespan is 17% lower; Average male lifespan is 19% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutations
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Dys
Homologs in other organisms
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (13405)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar