Saccharomyces cerevisiaeGenAge entry for DAP2 (Saccharomyces cerevisiae)

Gene information (ID: 1742)

Symbol
DAP2
Aliases
DPP2
Name
YHR028C
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
DAP2 deletion decreases mean and maximum replicative lifespan under ad libitum, and cancels the lifespan extending effect of moderate dietary restriction.
% change in max lifespan
Maximum lifespan is 36% lower.
% change in avg or median lifespan
Average lifespan is 19% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Dpp9
    GenDR gene manipulations
    • This gene is present as DAP2
    CellAge
    • A homolog of this gene for Homo sapiens is present as DPP4
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as DPP4

    Homologs in other organisms

    Caenorhabditis elegans
    dpf-3
    Caenorhabditis elegans
    dpf-1
    Caenorhabditis elegans
    dpf-2
    Danio rerio
    dpp6b
    Danio rerio
    fap
    Danio rerio
    dpp9
    Danio rerio
    dpp4
    Danio rerio
    DPP10
    Danio rerio
    dpp6a
    Drosophila melanogaster
    ome
    Drosophila melanogaster
    CG3744
    Drosophila melanogaster
    CG11034
    Drosophila melanogaster
    CG17684
    Drosophila melanogaster
    CG11319
    Drosophila melanogaster
    CG45002
    Homo sapiens
    FAP
    Homo sapiens
    DPP6
    Homo sapiens
    DPP10
    Homo sapiens
    DPP9
    Homo sapiens
    DPP8
    Homo sapiens
    DPP4
    Mus musculus
    Dpp10
    Mus musculus
    Dpp8
    Mus musculus
    Dpp9
    Mus musculus
    Fap
    Mus musculus
    Dpp6
    Mus musculus
    Dpp4
    Rattus norvegicus
    Dpp4
    Rattus norvegicus
    Dpp6
    Rattus norvegicus
    Dpp10
    Rattus norvegicus
    Dpp8
    Rattus norvegicus
    Fap
    Rattus norvegicus
    Dpp9
    Schizosaccharomyces pombe
    SPAC2E11.08

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (856423)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar