Saccharomyces cerevisiaeGenAge entry for ATG18 (Saccharomyces cerevisiae)

Gene information (ID: 1304)

Symbol
ATG18
Aliases
AUT10; CVT18; NMR1; SVP1
Name
AuTophaGy related
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean chronological lifespan strongly decreased in the a strain
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain by more than 50%
    % change in avg or median lifespan
    Mean chronological lifespan is more than 50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as atg-18
      CellAge
      • A homolog of this gene for Homo sapiens is present as WIPI1

      Homologs in other organisms

      Caenorhabditis elegans
      atg-18
      Danio rerio
      wipi1
      Danio rerio
      wipi2
      Danio rerio
      WIPI1 (1 of many)
      Drosophila melanogaster
      Atg18a
      Drosophila melanogaster
      Atg18b
      Homo sapiens
      WIPI2
      Homo sapiens
      WIPI1
      Mus musculus
      Wipi1
      Mus musculus
      Wipi2
      Rattus norvegicus
      Wipi2
      Rattus norvegicus
      Wipi1
      Schizosaccharomyces pombe
      atg18

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (850577)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar