Drosophila melanogasterGenAge entry for S6k (Drosophila melanogaster)

Gene information (ID: 583)

Symbol
S6k
Aliases
10539; 7084; CG10539; Dmel\CG10539; dp70s6k; Dp70s6k; Dp
Name
RPS6-p70-protein kinase
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Part of the TOR pathway involved in cell growth and size

Potential relevance to longevity and/or ageing

Observations
Expression of a dominant-negative form extended lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Dominant negative mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Rps6kb1
    • A homolog of this gene for Caenorhabditis elegans is present as rsks-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as TPK3
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as RPS6KB1

    Homologs in other organisms

    Caenorhabditis elegans
    rsks-1
    Danio rerio
    rps6kb1b
    Danio rerio
    rps6kb1a
    Homo sapiens
    RPS6KB2
    Homo sapiens
    RPS6KB1
    Mus musculus
    Rps6kb1
    Mus musculus
    Rps6kb2
    Rattus norvegicus
    Rps6kb2
    Rattus norvegicus
    Rps6kb1
    Saccharomyces cerevisiae
    TPK3

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (38654)
    Homologues
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    UniProt
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    Internet
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