Saccharomyces cerevisiaeGenAge entry for SET1 (Saccharomyces cerevisiae)

Gene information (ID: 1917)

Symbol
SET1
Aliases
KMT2; YTX1
Name
histone methyltransferase SET1
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of histone methyltransferase SET1 results in an decreased replicative lifespan.
% change in avg or median lifespan
Replicative lifespan is 29% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as E(z)
    • A homolog of this gene for Caenorhabditis elegans is present as set-2
    • A homolog of this gene for Caenorhabditis elegans is present as mes-2
    CellAge
    • A homolog of this gene for Homo sapiens is present as EZH2
    • A homolog of this gene for Homo sapiens is present as SETD1A
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as EZH2

    Homologs in other organisms

    Caenorhabditis elegans
    set-2
    Caenorhabditis elegans
    mes-2
    Caenorhabditis elegans
    set-16
    Danio rerio
    ezh2
    Danio rerio
    setd1ba
    Danio rerio
    ezh1
    Danio rerio
    kmt2cb
    Danio rerio
    kmt2bb
    Danio rerio
    kmt2ba
    Danio rerio
    kmt2d
    Danio rerio
    setd1bb
    Danio rerio
    setd1a
    Danio rerio
    kmt2ca
    Danio rerio
    kmt2a
    Drosophila melanogaster
    trx
    Drosophila melanogaster
    E(z)
    Drosophila melanogaster
    Lpt
    Drosophila melanogaster
    Set1
    Drosophila melanogaster
    trr
    Homo sapiens
    KMT2A
    Homo sapiens
    EZH1
    Homo sapiens
    EZH2
    Homo sapiens
    KMT2D
    Homo sapiens
    KMT2B
    Homo sapiens
    SETD1B
    Homo sapiens
    SETD1A
    Homo sapiens
    KMT2C
    Mus musculus
    Kmt2d
    Mus musculus
    Kmt2a
    Mus musculus
    Ezh2
    Mus musculus
    Setd1b
    Mus musculus
    RP23-325D10.3
    Mus musculus
    Kmt2c
    Mus musculus
    Setd1a
    Mus musculus
    Kmt2b
    Mus musculus
    Ezh1
    Rattus norvegicus
    Kmt2b
    Rattus norvegicus
    Kmt2d
    Rattus norvegicus
    Kmt2d
    Rattus norvegicus
    Kmt2c
    Rattus norvegicus
    Ezh2
    Rattus norvegicus
    Ezh1
    Rattus norvegicus
    Setd1b
    Rattus norvegicus
    Setd1a
    Rattus norvegicus
    Kmt2a
    Schizosaccharomyces pombe
    set1

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
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    Entrez Gene
    View on Entrez Gene database (856519)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar