- Symbol
- E(z)
- Aliases
- CG6502; Dmel\CG6502; E(Z); E(z)1; Ez; EZ; E[z]; l(3)1902;
- Name
- Enhancer of zeste
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Flies heterozygous for the protein null E(z)63 or the catalytically inactive E(z)731 mutation that were progeny of an out-cross to an Oregon-R (O-R) wild-type strain exhibited a substantially greater median life span than the O-R control (71% and 76%, respectively). When derived from an out-cross to a longer-lived Canton-S (C-S) wild-type strain, the median life span of E(z)63 heterozygotes was 33% longer than the C-S control
- % change in max lifespan
- Maximum lifespan is approximately 54% higher.
- % change in avg or median lifespan
- Median lifespan is 76% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutations
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SET1
- A homolog of this gene for Caenorhabditis elegans is present as mes-2
- CellAge
- A homolog of this gene for Homo sapiens is present as EZH2
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as EZH2
- Caenorhabditis elegans
- mes-2
- Danio rerio
- ezh2
- Danio rerio
- ezh1
- Homo sapiens
- EZH2
- Homo sapiens
- EZH1
- Mus musculus
- Ezh2
- Mus musculus
- Ezh1
- Rattus norvegicus
- Ezh2
- Rattus norvegicus
- Ezh1
- Saccharomyces cerevisiae
- SET1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (39203)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar