Mus musculusGenAge entry for Myc (Mus musculus)

Gene information (ID: 1876)

Symbol
Myc
Name
myelocytomatosis oncogene
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Haploinsufficient Myc mice are more active, have a higher metabolic rate and healthier lipid metabolism, and display resistance to several age-associated pathologies, including osteoporosis, cardiac fibrosis, and immunosenescence. Additionally, both male and female mutants live longer than the wild type.
% change in avg or median lifespan
Male median lifespan is ~10% higher; Female median lifespan is ~21%.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as dm
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MYC
    CellAge
    • A homolog of this gene for Homo sapiens is present as MYC

    Homologs in other organisms

    Danio rerio
    mycb
    Danio rerio
    myca
    Drosophila melanogaster
    dm
    Homo sapiens
    MYC
    Rattus norvegicus
    Myc

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (17869)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar