- Symbol
- dm
- Name
- diminutive
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Overexpression of dm (ortholog of the mammalian Myc) during larval development increases the frequency and the severity of somatic mutations, and shortens median lifespan by 42-47%. Maximum lifespan is 30-40% shorter. Contrastly, dm haploinsufficiency lowers the frequency of somatic mutations and extends lifespan by about 14%.
- % change in max lifespan
- Maximum lifespan is up to 40% lower.
- % change in avg or median lifespan
- Median lifespan is up to 47% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Myc
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MYC
- CellAge
- A homolog of this gene for Homo sapiens is present as MYC
- A homolog of this gene for Homo sapiens is present as MYCN
- Danio rerio
- mycb
- Danio rerio
- mycla
- Danio rerio
- mych
- Danio rerio
- myclb
- Danio rerio
- mycn
- Danio rerio
- myca
- Homo sapiens
- MYCN
- Homo sapiens
- MYC
- Homo sapiens
- MYCL
- Mus musculus
- Bmyc
- Mus musculus
- Mycn
- Mus musculus
- Mycl
- Mus musculus
- Myc
- Mus musculus
- Mycs
- Rattus norvegicus
- Mycn
- Rattus norvegicus
- Bmyc
- Rattus norvegicus
- Myc
- Rattus norvegicus
- Mycs
- Rattus norvegicus
- Mycl
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (31310)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for dm (Drosophila melanogaster)