GenAge entry for Akt2 (Mus musculus)
Gene information (ID: 2231)
- Symbol
- Akt2
- Name
- thymoma viral proto-oncogene 2
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Akt2-/- mice exhibited a 9.1% increase in mean lifespan. Median survival was 33 months for wild type mice and 36 months for Akt2-/- mice. However, the Akt2-/- mice showed increased cardiac hypertrophy.
- % change in avg or median lifespan
- Mean lifespan is 9% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
Homologs in other organisms
- Caenorhabditis elegans
- akt-2
- Caenorhabditis elegans
- akt-1
- Danio rerio
- akt2
- Danio rerio
- akt2l
- Drosophila melanogaster
- Akt1
- Homo sapiens
- AKT2
- Rattus norvegicus
- Akt2
- Saccharomyces cerevisiae
- SCH9
- Saccharomyces cerevisiae
- YPK1
- Saccharomyces cerevisiae
- YPK2
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (11652)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar