Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ATG7

Gene Information (Entrez Gene ID: 10533)

Symbol
ATG7
Aliases
GSA7 APG7L APG7-LIKE
Name
autophagy related 7
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
10533

Potential relevance to dietary restriction and ageing

Observations

Methionine restriction (a form of dietary restriction), aquired through MET2 or MET17 knockout, enhances lifespan in yeast. In both MET2 and MET17 models, this lifespan extension is abolished by the deletion of ATG5, ATG7, or ATG8 lifespan reaching comparable or even lower survival levels to those of controls.

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Atg7
    • A homolog of this gene for Caenorhabditis elegans is present as atg-7
    GenDR gene manipulations
    • A homolog of this gene for Caenorhabditis elegans is present as atg-7

    Homologs

    Homo sapiens
    ATG7
    Homo sapiens
    ATG7
    Homo sapiens
    ATG7
    Homo sapiens
    ATG7
    Homo sapiens
    ATG7
    Homo sapiens
    ATG7
    Homo sapiens
    ATG7

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 10533
    Homologues
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    UniProt
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    Internet
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