Drosophila melanogasterGenAge entry for Atg7 (Drosophila melanogaster)

Gene information (ID: 21)

Symbol
Atg7
Aliases
atg-7; atg7; CG5489; Dmel\CG5489
Name
Autophagy-specific gene 7
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Involved in autophagy

Potential relevance to longevity and/or ageing

Observations
Knockouts are short-lived and hypersensitive to nutrient and oxidative stress. There is a 30% reduction in maximal lifespan.
% change in max lifespan
Maximal lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Mutants are hypersensitive to oxidative stress and short lived.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Mutation
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as atg-7
      • A homolog of this gene for Saccharomyces cerevisiae is present as ATG7
      GenDR gene manipulations
      • A homolog of this gene for Saccharomyces cerevisiae is present as ATG7
      • A homolog of this gene for Caenorhabditis elegans is present as atg-7

      Homologs in other organisms

      Caenorhabditis elegans
      atg-7
      Danio rerio
      uncharacterized_E7F5
      Homo sapiens
      ATG7
      Mus musculus
      Atg7
      Rattus norvegicus
      Atg7
      Saccharomyces cerevisiae
      ATG7
      Schizosaccharomyces pombe
      atg7

      External links

      FlyBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (37141)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar