GenAge entry for lgg-1 (Caenorhabditis elegans)
Gene information (ID: 955)
- Symbol
- lgg-1
- Name
- LC3, GABARAP and GATE-16 family
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- 43% mean LS reduction
- % change in avg or median lifespan
- Average lifespan is 43% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- 12% maximal lifespan reduction compared to wild-type by RNAi from the beginning of life. Postdevelopmental RNAi caused a maximum lifespan reduction by 10% compared to wild-type.
- % change in max lifespan
- Maximum lifespan is 10-12% higher.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG8
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as GABARAP
Homologs in other organisms
- Danio rerio
- gabarapb
- Danio rerio
- gabarapa
- Drosophila melanogaster
- Atg8b
- Drosophila melanogaster
- Atg8a
- Homo sapiens
- GABARAP
- Mus musculus
- Gabarap
- Rattus norvegicus
- Gabarap
- Saccharomyces cerevisiae
- ATG8
- Schizosaccharomyces pombe
- atg8
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (174050)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar