- Symbol
- Socs2
- Aliases
- hg; JAB; CIS2; Cish2; SSI-2; SOCS-2; AI527257; AW108012; 8
- Name
- Suppressor of cytokine signaling 2
- Organism
- Mus musculus (AnAge)
- Observations
- Mutant mice exhibited a reduced mean and maximal lifespan compared to wild type. The lack of SOCS2 expression in the high-growth mouse also increases plasma IGF1, and reduces plasma and pituitary GH levels.
- % change in max lifespan
- Maximum lifespan is 14% lower.
- % change in avg or median lifespan
- Average lifespan is 35% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutations
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as SOCS2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOCS2
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as SOCS2
- Danio rerio
- socs2
- Drosophila melanogaster
- Socs44A
- Homo sapiens
- SOCS2
- Rattus norvegicus
- AC124896.1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (216233)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar