Saccharomyces cerevisiaeGenAge entry for GPA2 (Saccharomyces cerevisiae)

Gene information (ID: 319)

Symbol
GPA2
Aliases
SSP101
Name
Gpa2p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Encodes G-protein alpha subunit, which acts in parallel to Ras pathway to activate adenylate cyclase

Potential relevance to longevity and/or ageing

Observations
Deletion increases lifespan by about 50%.
% change in avg or median lifespan
Lifespan is about 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as gpa-1
      • A homolog of this gene for Caenorhabditis elegans is present as gpa-3
      • A homolog of this gene for Caenorhabditis elegans is present as odr-3
      • A homolog of this gene for Caenorhabditis elegans is present as egl-30
      • A homolog of this gene for Caenorhabditis elegans is present as goa-1
      GenDR gene manipulations
      • This gene is present as GPA2
      • A homolog of this gene for Schizosaccharomyces pombe is present as gpa2
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as GNA14

      Homologs in other organisms

      Caenorhabditis elegans
      gpa-4
      Caenorhabditis elegans
      goa-1
      Caenorhabditis elegans
      gpa-7
      Caenorhabditis elegans
      gpa-3
      Caenorhabditis elegans
      odr-3
      Caenorhabditis elegans
      gpa-1
      Caenorhabditis elegans
      egl-30
      Caenorhabditis elegans
      gpa-16
      Danio rerio
      gnao1a
      Danio rerio
      gnao1b
      Danio rerio
      gnai1
      Danio rerio
      gnai2b
      Danio rerio
      gnaia
      Danio rerio
      gna15.3
      Danio rerio
      gnat1
      Danio rerio
      gnat2
      Danio rerio
      gna15.1
      Danio rerio
      gnai2a
      Danio rerio
      gnaq
      Danio rerio
      gna15.2
      Danio rerio
      gnai3
      Danio rerio
      GNAZ
      Danio rerio
      gnav1
      Danio rerio
      gna11b
      Danio rerio
      gna14a
      Danio rerio
      gna11a
      Danio rerio
      gna14
      Drosophila melanogaster
      CG30054
      Drosophila melanogaster
      CG17760
      Drosophila melanogaster
      Galphai
      Drosophila melanogaster
      Galphao
      Drosophila melanogaster
      Galphaq
      Homo sapiens
      GNAI2
      Homo sapiens
      GNAI1
      Homo sapiens
      GNAT3
      Homo sapiens
      GNAT2
      Homo sapiens
      GNA15
      Homo sapiens
      GNAI3
      Homo sapiens
      GNA14
      Homo sapiens
      GNAO1
      Homo sapiens
      GNA11
      Homo sapiens
      GNAZ
      Homo sapiens
      GNAT1
      Homo sapiens
      GNAQ
      Mus musculus
      Gnaq
      Mus musculus
      Gnao1
      Mus musculus
      Gnat1
      Mus musculus
      Gnai3
      Mus musculus
      Gnat2
      Mus musculus
      Gna14
      Mus musculus
      Gna11
      Mus musculus
      Gnat3
      Mus musculus
      Gnaz
      Mus musculus
      Gna15
      Mus musculus
      Gnai1
      Mus musculus
      Gnai2
      Rattus norvegicus
      Gnaz
      Rattus norvegicus
      Gnat1
      Rattus norvegicus
      Gnaq
      Rattus norvegicus
      Gna14
      Rattus norvegicus
      Gnat3
      Rattus norvegicus
      Gnat2
      Rattus norvegicus
      Gnai3
      Rattus norvegicus
      Gnai1
      Rattus norvegicus
      Gnao1
      Rattus norvegicus
      Gna11
      Rattus norvegicus
      Gnai2
      Rattus norvegicus
      Gna15
      Schizosaccharomyces pombe
      gpa2

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
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      Entrez Gene
      View on Entrez Gene database (856741)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar