Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: GPA2

Gene Information (Entrez Gene ID: 856741)

Symbol
GPA2
Aliases
SSP101
Name
G Protein Alpha subunit 2
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
856741

Potential relevance to dietary restriction and ageing

Observations

Deletion of GPA2 increases mean and maximum replicative lifespan by 40% and 26%, respectively. Deletion of GPA2 extends replicative lifespan by reducing cAMP-PKA activity and provides a genetic model for DR [2260].

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as gpa-1
    • A homolog of this gene for Caenorhabditis elegans is present as gpa-3
    • This gene is present as GPA2
    • A homolog of this gene for Caenorhabditis elegans is present as odr-3
    • A homolog of this gene for Caenorhabditis elegans is present as egl-30
    • A homolog of this gene for Caenorhabditis elegans is present as goa-1
    GenDR gene manipulations
    • A homolog of this gene for Schizosaccharomyces pombe is present as gpa2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as GNA14

    Homologs

    Caenorhabditis elegans
    gpa-4
    Caenorhabditis elegans
    goa-1
    Caenorhabditis elegans
    gpa-7
    Caenorhabditis elegans
    gpa-3
    Caenorhabditis elegans
    odr-3
    Caenorhabditis elegans
    gpa-1
    Caenorhabditis elegans
    egl-30
    Caenorhabditis elegans
    gpa-16
    Danio rerio
    gnao1a
    Danio rerio
    gnao1b
    Danio rerio
    gnai1
    Danio rerio
    gnai2b
    Danio rerio
    gnaia
    Danio rerio
    gna15.3
    Danio rerio
    gnat1
    Danio rerio
    gnat2
    Danio rerio
    gna15.1
    Danio rerio
    gnai2a
    Danio rerio
    gnaq
    Danio rerio
    gna15.2
    Danio rerio
    gnai3
    Danio rerio
    GNAZ
    Danio rerio
    gnav1
    Danio rerio
    gna11b
    Danio rerio
    gna14a
    Danio rerio
    gna11a
    Danio rerio
    gna14
    Drosophila melanogaster
    CG30054
    Drosophila melanogaster
    CG17760
    Drosophila melanogaster
    Galphai
    Drosophila melanogaster
    Galphao
    Drosophila melanogaster
    Galphaq
    Homo sapiens
    GNAI2
    Homo sapiens
    GNAI1
    Homo sapiens
    GNAT3
    Homo sapiens
    GNAT2
    Homo sapiens
    GNA15
    Homo sapiens
    GNAI3
    Homo sapiens
    GNA14
    Homo sapiens
    GNAO1
    Homo sapiens
    GNA11
    Homo sapiens
    GNAZ
    Homo sapiens
    GNAT1
    Homo sapiens
    GNAQ
    Mus musculus
    Gnaq
    Mus musculus
    Gnao1
    Mus musculus
    Gnat1
    Mus musculus
    Gnai3
    Mus musculus
    Gnat2
    Mus musculus
    Gna14
    Mus musculus
    Gna11
    Mus musculus
    Gnat3
    Mus musculus
    Gnaz
    Mus musculus
    Gna15
    Mus musculus
    Gnai1
    Mus musculus
    Gnai2
    Rattus norvegicus
    Gnaz
    Rattus norvegicus
    Gnat1
    Rattus norvegicus
    Gnaq
    Rattus norvegicus
    Gna14
    Rattus norvegicus
    Gnat3
    Rattus norvegicus
    Gnat2
    Rattus norvegicus
    Gnai3
    Rattus norvegicus
    Gnai1
    Rattus norvegicus
    Gnao1
    Rattus norvegicus
    Gna11
    Rattus norvegicus
    Gnai2
    Rattus norvegicus
    Gna15
    Schizosaccharomyces pombe
    gpa2

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    ID 856741
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar