- Symbol
- Mpk2
- Aliases
- CG5475; D-MPK2; D-p38; D-p38; MAPK; D-p38a; D-P38a; Dmel\
- Name
- CG5475-PA
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- p38K-DKO adult flies appeared normal on eclosion but had a severely reduced lifespan. ingle mutants of p38Ka (p38Kadel) or p38Kb (p38Kd45) also had significantly reduced lifespan, with the loss of p38Kb resulting in a stronger phenotype.
- % change in avg or median lifespan
- Average lifespan is 40% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MAPK14
- GenDR gene manipulations
- A homolog of this gene for Schizosaccharomyces pombe is present as sty1
- CellAge
- A homolog of this gene for Homo sapiens is present as MAPK12
- A homolog of this gene for Homo sapiens is present as MAPK14
- Caenorhabditis elegans
- pmk-1
- Caenorhabditis elegans
- pmk-2
- Danio rerio
- mapk14b
- Danio rerio
- mapk11
- Danio rerio
- mapk12b
- Danio rerio
- mapk13
- Danio rerio
- zgc:171775
- Danio rerio
- mapk12a
- Danio rerio
- mapk14a
- Homo sapiens
- MAPK12
- Homo sapiens
- MAPK13
- Homo sapiens
- MAPK14
- Homo sapiens
- MAPK11
- Mus musculus
- Mapk13
- Mus musculus
- Mapk11
- Mus musculus
- Mapk12
- Mus musculus
- Mapk14
- Rattus norvegicus
- Mapk12
- Rattus norvegicus
- Mapk13
- Rattus norvegicus
- Mapk14
- Rattus norvegicus
- Mapk11
- Saccharomyces cerevisiae
- HOG1
- Schizosaccharomyces pombe
- sty1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (42866)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar