- Symbol
- odr-3
- Name
- ODoRant response abnormal
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- G Protein, Alpha subunit
- Observations
- Worms with a odr-3 loss-of-function mutation display an increased lifespan in a temperature-independent manner.
- % change in avg or median lifespan
- Mean lifespan is up to 27% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Loss-of-function mutation extended mean lifespan by 10-30% but not maximum lifespan. Life-extension was dependent on daf-16 but cumulative with daf-2 mutations.
- % change in avg or median lifespan
- Average lifespan is 10-30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- Saccharomyces cerevisiae
- GPA2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (179806)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for odr-3 (Caenorhabditis elegans)