Saccharomyces cerevisiaeGenAge entry for TOS8 (Saccharomyces cerevisiae)

Gene information (ID: 1285)

Symbol
TOS8
Name
Target Of Sbf
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan increased by 35% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 35% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as unc-62
      LongevityMap
      • A homolog of this gene for Homo sapiens is present as PKNOX2

      Homologs in other organisms

      Caenorhabditis elegans
      unc-62
      Danio rerio
      pknox1.1
      Danio rerio
      pknox2
      Danio rerio
      tgif1
      Danio rerio
      meis2b
      Danio rerio
      meis2a
      Danio rerio
      meis3
      Danio rerio
      pknox1.2
      Danio rerio
      meis1b
      Danio rerio
      meis1a
      Drosophila melanogaster
      hth
      Drosophila melanogaster
      achi
      Drosophila melanogaster
      vis
      Homo sapiens
      TGIF1
      Homo sapiens
      PKNOX1
      Homo sapiens
      MEIS2
      Homo sapiens
      MEIS1
      Homo sapiens
      TGIF2LY
      Homo sapiens
      TGIF2LX
      Homo sapiens
      MEIS3
      Homo sapiens
      TGIF2
      Homo sapiens
      PKNOX2
      Mus musculus
      Tgif2lx2
      Mus musculus
      Pknox2
      Mus musculus
      Pknox1
      Mus musculus
      Tgif1
      Mus musculus
      Meis3
      Mus musculus
      Meis2
      Mus musculus
      Meis1
      Mus musculus
      Tgif2
      Mus musculus
      Tgif2lx1
      Rattus norvegicus
      Tgif2
      Rattus norvegicus
      Meis3
      Rattus norvegicus
      Tgif1
      Rattus norvegicus
      Pknox2
      Rattus norvegicus
      Meis1
      Rattus norvegicus
      Pknox1
      Rattus norvegicus
      Tgif2lx2
      Rattus norvegicus
      Tgif2-ps1
      Rattus norvegicus
      Meis2

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
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      Entrez Gene
      View on Entrez Gene database (852783)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar