Caenorhabditis elegansGenAge entry for ccr-4 (Caenorhabditis elegans)

Gene information (ID: 97)

Symbol
ccr-4
Name
CCR (yeast CCR4/NOT complex component) homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Alcohol dehydrogenase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 33% in wild type animals, 37% in a daf-2 background and 44% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 33% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as CNOT6

    Homologs in other organisms

    Danio rerio
    cnot6l
    Danio rerio
    cnot6a
    Danio rerio
    cnot6b
    Drosophila melanogaster
    twin
    Homo sapiens
    CNOT6L
    Homo sapiens
    CNOT6
    Mus musculus
    Cnot6
    Mus musculus
    Cnot6l
    Rattus norvegicus
    Cnot6l
    Rattus norvegicus
    Cnot6
    Saccharomyces cerevisiae
    CCR4
    Schizosaccharomyces pombe
    ccr4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178184)
    Homologues
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    UniProt
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    Internet
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