Caenorhabditis elegansGenAge entry for pdk-1 (Caenorhabditis elegans)

Gene information (ID: 499)

Symbol
pdk-1
Name
PDK-class protein kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Serine/threonine kinase

Potential relevance to longevity and/or ageing

Observations
Loss-of-function alleles extend lifespan by 60%.
% change in avg or median lifespan
Lifespan is 60% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as PKH1
    • A homolog of this gene for Saccharomyces cerevisiae is present as PKH3
    • A homolog of this gene for Saccharomyces cerevisiae is present as PKH2
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PDPK1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as PKH2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as PDPK1
    CellAge
    • A homolog of this gene for Homo sapiens is present as PDPK1

    Homologs in other organisms

    Danio rerio
    pdpk1b
    Danio rerio
    pdpk1a
    Drosophila melanogaster
    Pdk1
    Homo sapiens
    PDPK1
    Mus musculus
    Pdpk1
    Rattus norvegicus
    Pdpk1
    Saccharomyces cerevisiae
    PKH1
    Saccharomyces cerevisiae
    PKH2
    Saccharomyces cerevisiae
    PKH3
    Schizosaccharomyces pombe
    ppk21

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180475)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar