- Symbol
- Pcmt
- Aliases
- CG2152; Dmel\CG2152; dPIMT; pcmt; Pimt; PIMT
- Name
- Protein-L-isoaspartate (D-aspartate) O-methyltransferase
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Protein repair
- Observations
- Overexpression extended lifespan by 32-39% at 29 degrees but not at 25 degrees.
- % change in avg or median lifespan
- Lifespan is 32-39% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Adult lifespan of flies with overexpressed pcmt was extended.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as pcm-1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as PCMT1
- Caenorhabditis elegans
- pcm-1
- Danio rerio
- pcmtl
- Danio rerio
- pcmt
- Homo sapiens
- PCMT1
- Mus musculus
- Pcmt1
- Rattus norvegicus
- Pcmt1
- Schizosaccharomyces pombe
- pcm2
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (40668)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Pcmt (Drosophila melanogaster)