Saccharomyces cerevisiaeGenAge entry for KSS1 (Saccharomyces cerevisiae)

Gene information (ID: 397)

Symbol
KSS1
Name
Kss1p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Proliferation, differentiation, transcription regulation and development

Potential relevance to longevity and/or ageing

Observations
Deletion resulted in increased sensitivity to heat shock and oxidative stress and a 33% reduction in median lifespan.
% change in avg or median lifespan
Median lifespan is 33% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as mpk-1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MAPK3
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MAPK1
    • A homolog of this gene for Homo sapiens is present as MAPK3

    Homologs in other organisms

    Caenorhabditis elegans
    C05D10.2
    Caenorhabditis elegans
    lit-1
    Caenorhabditis elegans
    F09C12.2
    Caenorhabditis elegans
    mpk-2
    Caenorhabditis elegans
    mpk-1
    Danio rerio
    mapk4
    Danio rerio
    nlk1
    Danio rerio
    mapk3
    Danio rerio
    mapk1
    Danio rerio
    mapk7
    Danio rerio
    mapk15
    Danio rerio
    mapk6
    Danio rerio
    nlk2
    Drosophila melanogaster
    rl
    Drosophila melanogaster
    Erk7
    Drosophila melanogaster
    nmo
    Homo sapiens
    MAPK4
    Homo sapiens
    MAPK3
    Homo sapiens
    MAPK6
    Homo sapiens
    MAPK15
    Homo sapiens
    MAPK1
    Homo sapiens
    MAPK7
    Homo sapiens
    NLK
    Mus musculus
    Mapk1
    Mus musculus
    Mapk3
    Mus musculus
    Mapk7
    Mus musculus
    Mapk15
    Mus musculus
    Mapk4
    Mus musculus
    Mapk6
    Mus musculus
    Nlk
    Rattus norvegicus
    Mapk3
    Rattus norvegicus
    LOC100912585
    Rattus norvegicus
    Mapk7
    Rattus norvegicus
    LOC100912585
    Rattus norvegicus
    Mapk1
    Rattus norvegicus
    Nlk
    Rattus norvegicus
    Mapk4
    Rattus norvegicus
    Mapk6
    Rattus norvegicus
    Mapk15
    Schizosaccharomyces pombe
    cka1

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (852931)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar